Technology Offerings

Technology Offerings

New Head Measurement Method Enhances Cranial Treatment

The presented innovation is a new method for head measurement which works with an app. Scopes of application of the new method can be found in the field of diagnosis and treatment of cranial deformations, e.g. the helmet therapy.

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Lugdunin and Derivatives – a New Class of Antibiotics Against Gram-Positive Bacteria

Among Gram-positive bacteria are some of the most dangerous pathogens for humans. Especially Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for a high percentage of hospital-acquired and deadly infections.
We have identified a naturally human-associated bacterial antibiotic producer strain (S. lugdunensis IVK28 wild type), which may act as a probiotic cure before patients enter hospital. Its application could avoid costly decolonization of human commensal bacteria before surgery.
From this bacterium we furthermore isolated a previously unknown class of peptide related structures with high potential as new antibiotics. Total chemical synthesis has been established.
The main compound Lugdunin shows very high potential against MRSA and other highly-resistant species like Enterococcus faecalis, E. faecium (VRE), Streptococcus pneumoniae and Listeria monocytogenes.
A patent application covering the chemical structures, the genetic background of the producer strain and the bioactivity of the new substances has been filed.

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New Multi-Well Plate Enhances Tissue-Based Drug Screening

More than 90% of drugs passing through today's preclinical cell cultures studies fail to meet the desired efficacy or safety. Tissue engineering has undergone exciting progress and more similar to the in vivo situation. Scientists at University of Göttingen developed a new device for automated tissue engineering & drug testing.

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New Implantable Electrode Enhances Electromyogram Detection

We offer a electromyogramm (EMG) electrode for the chronic percutaneous implantation for a robust and reliable electromyogram detection in myolectric control of e.g. prosthesis. It solves reliability issues related to skin conditions, electrode lift-offs and variations of electrode positioning. No wireless transmission is needed, they can be directly connected external amplifiers.

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Modular Immunoglobulins Boost T-Cell Activation in Her2 Therapy

Domain-exchanged complete antibody composed of the Fc fragment and variable domains where CH1 and CL domains have been exchanged for a pair of CH3 domains.

Modular immunoglobulins composed of Fab-like fragment with HerceptinVL and VH region and CH3 domains and an unmodified Fc fragment are described. Novel is an increased binding to FcR³III, which leads to potentiated T-cell activation upon binding to a Her2-positive cell line

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New Aluminum-Based Photo Acid Generator Boosts Cationic Polymerization

A new aluminum based photo acid generator which is easy to synthesize[2, 3] (sulphonium as weil as iodonium salt) at high yields is described. The educts are inexpensive and commercially available. This high stability and the abandonment of any heavy metals in our novel PAG prompts a low toxicity.

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Tramkopftemperierung innengedämmter Außenwände

Die Erfindung dient zur Verhinderung von Tauwasserbildung an den Tramköpfen einer Holzbalkendecke bei Innendämmung. Die Wärmeleitbleche ermöglichen eine energiesparende Temperierung des Tramkopfs und somit eine dauerhafte Sanierung und Erhaltung der Tramdecke.

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Wooden Beam Temperature Control for Insulated Interiors

The invention prevents the condensation of water forming on the traverse heads of a wooden beam ceiling when the building is insulated internally. Using heat conduction plates enables energy-saving temperature control of the beam head area and thus durable renovation of a wooden beam ceiling.

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Thin Film Solar Cells: Sustainable Copper Oxide Innovations

The new type of solar cells contains copper oxide phases as a photovoltaic absorber film in combination with e.g. AlGaN, ZnMgO, or ZnBeO thin film. These are non-toxic and their production is possible in industrial scale (e.g. using the cathode sputtering technique) and with low energy consumption.

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New Salmonella DIVA Vaccine for Pigs Boosts Food Safety

Food-borne salmonella infections are mostly arising from poultry or pigs. While actions have been taken for poultry there has only been minor success for a pig vaccine. Scientists at the University of Veterinary Medicine Hanover developed a marker vaccine for pigs, which allows differentiation of vaccinated and infected animals.

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Magnetic Closure System Enhances Container Safety and Convenience

The present innovation provides lid and housing of a container with magnets in order to connect those reversibly and safely with each other.

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SOTOS – Silent Operating Theatre Optimisation System

New technical solution to manage targeted communication between team members and to minimize noise in the operating theatre. This reduces stress for the operating staff and concomitantly mistakes. We offer the Silent Operating Theatre Optimisation System – “SOTOS”. Prototype tested and available.

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New Device Monitors Soot Deposition in Power Plant Boilers

The Institute of Combustion and Power Plant Technology (IFK) of the University of Stuttgart has developed a measuring device for use in coal power plants. The device allows for permanent monitoring of the conditions inside the boiler, particularly of soot deposition.
Besides determining the deposition rate inside the boiler, growth characteristics, adhesion, ash qualities and waste disposal behavior with deposit as well as the extent to which these can be cleaned using soot blowers can be judged. Thus, the measuring device can indicate potential for optimization, e.g. of coal compositon in the fuel feed.
The prototype has been tested successfully.

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X-ray and Gamma-ray sources based on relativistic Thomson backscattering

The new method allows high laser intensities of any level. Thus, the novel backscattering sources generate X and Gamma-radiation with highest brilliance and intensity and low bandwidth.

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In Vivo VEGF Monitoring Tool for Retinal Disorders

The technology comprises a method for determination of VEGF (vascular endothelial growth factor) concentration directly in vivo in the eye by use of an implantable, semi-permeable biosensor.

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New Synthetic Compounds Boost Immunity Against Leishmaniasis, TB

The current treatments for tuberculosis and leishmaniosis have many drawbacks: long treatment duration,appearance of resistances,toxic side effects. Our new treatment suggests an immune activator based on a synthetic analogue of an active glycolipid.

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