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H3.3 Mutations Linked to Pediatric Brain Cancer Insights

The identification of two H3.3 mutations allow the categorization of pediatric brain cancer patients into patients with grade IV pediatric GBM (P<0.0001) and grade III pediatric anaplastic astrocytoma (p<0.0078) and diffuse intrinsic diffuse intrinsic pontine gliomas. Occurrence of these mutations is linked to lower survival rate and help physicians in the clinical decision making process.

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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
Phone: +49-6221-42 2955

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Dr. Ruth Herzog

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