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Innovative Monoclonal Antibodies Target C3a Receptor

Scientists at the University of Göttingen developed different monoclonal antibodies directed against the human / rat C3a-receptor. C3aR functions as a receptor for the C3a fragment of the complement factor C3, but also binds C4a. C3a binding to the C3a-receptor causes mast cell degranulation (anaphylatoxin).

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