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DNA and RNA Aptamers Target Soluble IL-6 Receptor Effectively

The invention concerns DNA- and RNA-aptamers with high affinity and specificity for the human soluble IL-6-receptor with no or very low immunogenicity. These aptamers are very promising substances to treat or prevent diseases involving the IL-6-receptor, such as inflammation, cancer or infections. Furthermore, they can be easily and cost-efficiently produced and stored.

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