Technique used to shrink tumors, delay their growth
A team of Vanderbilt-Ingram Cancer Center scientists shrunk tumors or delayed their growth in animal studies by using radiation to enable a drug to “zero in” and block the tumor blood vessels.
The work, reported in the January issue of the journal Cancer Cell, is a model for what might be achieved in patients by using radiation to activate drug targets in tumors. “We can now use combinations of chemotherapy and radiation to
New pathway presents target for medication development
Brain molecules similar to the active compound in marijuana help to regulate alcohol consumption, according to new reports by scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda, Maryland, and a separate NIAAA-supported group at several New York state research institutions.
In studies conducted with a strain of mice known to have a high preference for alcohol, the scientists found great
Treatment with two medications that suppress the immune system, rituximab and cyclophosphamide, appears to have cured one woman of an otherwise untreatable case of the blood disease known as thrombotic thrombocytopenic purpura (TTP). The findings support the theory that TTP is an autoimmune disease, and not only provide insight into diagnosis and treatment, but also reveal clues about blood clotting and autoimmune diseases in general.
“In this particular patient who did not respond to stand
An enzyme found only in the liver and intestines may play a crucial role in the development of hardening of the arteries — or atherosclerosis, a research team from Wake Forest University Baptist Medical Center and the University of California, San Francisco, report in the Proceedings of the National Academy of Sciences.
The narrowing of arteries through atherosclerosis is a major contributor to heart attacks and strokes.
The confirmation of the relationship between the enzyme, AC
Next-Generation IT Platform for Topological Proteomics to be Created
MelTec GmbH and the Fraunhofer Institute for Applied Information Technology FIT today signed a collaboration agreement to develop an information technology platform for the management and interpretation of high-throughput experiments analysing protein networks of whole cells in situ, also known as topological proteomics or toponomics. MelTec continuously generates large data sets to decipher the toponome of cells an
atugen AG, a private company focused on the elucidation of disease pathways, today announced the identification of a novel cancer target that appears to play an important role in tumor growth and metastasis. atugen’s research group has demonstrated that inhibition of the novel target, Atu027, which has homology to protein kinases, results in blockage of tumor growth of human prostate carcinoma cells in orthotopic mouse models. atugen has demonstrated that human prostate tumor cells engineered to expr
Precisely measuring the energy states of individual atoms has been a historical challenge for physicists due to atomic recoil. When an atom interacts with a photon, the atom “recoils” in…
The technique opens possibilities for exploring exotic states of matter and building new quantum materials. Proximity is key for many quantum phenomena, as interactions between atoms are stronger when the…
Research at the south pole studied the mysterious quantum structure of space and time. Einstein’s theory of general relativity explains that gravity is caused by a curvature of the directions…
New sensor is six orders of magnitude more sensitive than the next best thing. A research team at Pitt led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich…
New research shows how tiny plant-like organisms hitch a ride on ocean currents to reach darker and deeper depths, where they impact carbon cycling and microbial dynamics in the subtropical…
…without the application of phytohormones. Researchers develop a novel plant regeneration approach by modulating the expression of genes that control plant cell differentiation. For ages now, plants have been the…
Charge-recharge cycling of lithium-superrich iron oxide, a cost-effective and high-capacity cathode for new-generation lithium-ion batteries, can be greatly improved by doping with readily available mineral elements. The energy capacity and…
Engineers in Australia have found a new way to make power-pole insulators resistant to fire and electrical sparking, promising to prevent dangerous pole-top fires and reduce blackouts. Pole-top fires pose…
Potential alternative to widely used contrast agent gadolinium. Some of the world’s greatest discoveries happened by accident. While the discovery of diamond dust’s potential as a future MRI contrast agent…
A four-legged robot trained with machine learning by EPFL researchers has learned to avoid falls by spontaneously switching between walking, trotting, and pronking – a milestone for roboticists as well…
TUM professor uses ChatGPT for choreographies with flying robots. Prof. Angela Schoellig has proved that large language models can be used safely in robotics. ChatGPT develops choreographies for up to…
Compact, low-power system opens doors for photon-efficient drone and satellite-based environmental monitoring and mapping. Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D…