New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
This means the type of cell obtained from an individual patient to make pluripotent stem cells, determines what can be best done with them. For example, to…
They are one of the great hopes for target-oriented treatment approaches: the so-called small interfering RNA-molecules, siRNA. These are able to mute specific…
Researchers at the Max Planck Institute of Biochemistry in Martinsried near Munich have recently uncovered a previously unknown mechanism explaining how this…
A new National Science Foundation-supported project will provide computational tools designed to help identify and characterize the gene diversity of the…
By comparing patterns of genetic code from the brain tissue of alcoholics and nonalcoholics, the researchers discovered a particular set of genes co-expressed…
If further studies prove the variation to cause fibrosis (scarring) in the kidneys of transplant recipients, researchers may be able to use it to better screen…
Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research…
Whenever muscles contract, so-called ryanodine receptors come into play. Calcium ions, which are ultimately responsible for the contraction of muscle cells,…
Not in all cases where nature and biodiversity conservation is intended, species protection is the outcome. The ambitious political target e.g. of the German…
Most people with Gorlin syndrome have a change in a gene called PTCH1, but the new research has revealed that changes in a gene called SUFU also cause Gorlin…
The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for…
Today, ray-finned fish, which belong to the bony fish, are by far the most biodiverse fish group in both salt- and freshwater. Their spectacular variety of…
The vitamin supply provided by the symbionts directly influences the gene regulation of their host: If the bacterial associates are absent, the bugs show a…
Alzheimer's disease is the most common form of dementia. As many as 5 million Americans are affected, a number expected to grow to 14 million by 2050,…
Cannabinoid receptors are normally activated by compounds in the brain called endocannabinoids, the most abundant of which is 2-AG. They also are “turned on”…
Physicians at Brigham and Women's Hospital in Boston performed the country's first full-face transplantation in 2011 and have subsequently completed four…
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