Physicians have been concerned that relatively new prescription medications called statins, which are being increasingly prescribed to reduce blood cholesterol levels, might also decrease reproductive hormone levels and cause women of child-bearing age to be less fertile.

A study headed by researchers at Cedars-Sinai Medical Center in Los Angeles found that neither the use of statins nor low blood cholesterol levels significantly affected reproductive hormone levels in pre-, peri-, or postm

Scientists find key embryonic stem cell gene

Scientists have identified a gene that is required during early mammalian embryogenesis to maintain cellular pluripotency – the ability of an embryonic cell to develop into virtually any cell type of the adult animal. This discovery by Dr. Robin Lovell-Badge and colleagues at the MRC National Institute for Medical Research (London, UK) that the Sox2 gene is necessary to sustain the developmental plasticity of embryonic cells sheds new light

When members of two species compete directly with each other, scientists believe the one that rolls with the evolutionary punches and adapts most quickly has the upper hand. But new evidence suggests that in relationships that benefit both species, the one that evolves more slowly has the advantage.

“The idea that has been dominant for the last couple of decades is that when two species co-evolve, they try to outrun each other,” said Carl Bergstrom, a University of Washington assistant zoolo

While promising the possibility of hardier crops and a larger, more robust food supply for the world, worries continue over the effect genetically engineered plants might have on the environment. One fear is over the movement of altered genes from domesticated populations to the wild and the effect of these “escaped” genes on ecosystems. In a study published in the December issue of Ecological Applications, Charity Cummings (University of Kansas), Helen Alexander (University of Kansas), Allison Snow

An experimental drug designed to cut off a tumor’s blood supply showed promising results in patients with advanced colorectal cancer when paired with standard chemotherapy, according to a UCLA Jonsson Cancer Center study published in the Jan. 1 issue of the Journal of Clinical Oncology.

The results of this and subsequent studies of the experimental drug Avastin could change the way oncologists treat patients with this devastating form of cancer, said Dr. Fairooz Kabbinavar, a Jonsson C

For newly diagnosed multiple myeloma; Previously scorned thalidomide gives new option for patients with difficult-to-treat cancer

A recent study conducted at The University of Texas M. D. Anderson Cancer Center shows that patients with multiple myeloma, a cancer of the bone marrow, were more likely to achieve remission when treated with a combination of drugs that included thalidomide, a medicine that had previously been shelved for causing birth defects.

Donna Weber, M.D., a

A beer a day may help keep heart attacks away, according to a group of Israeli researchers. In preliminary clinical studies of a group of men with coronary artery disease, the researchers showed that drinking one beer (12 ounces) a day for a month produced changes in blood chemistry that are associated with a reduced risk of heart attack.

Their study adds to growing evidence that moderate alcohol consumption may reduce the risk of heart disease, the number one killer in the United States. T

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined the molecular machinery that triggers normal cardiac muscle growth and survival, and have linked defects in this complex to an inherited form of human cardiomyopathy, a type of heart failure where an enlarged heart loses its ability to pump blood.

Published in the December 27, 2002 issue of the journal Cell, the study also identifies a subset of German cardiomyopathy patients with a specific gene

Unexplained and severe tinnitus–a ringing or buzzing in the ears–can be temporarily reduced in some patients by “jamming” the brain’s electrical activity with focused magnetic stimulation, according to a preliminary study to be published December 23, 2002 in the online edition of the Annals of Neurology. The results confirm that some phantom sounds are generated by abnormal activity in the brain itself.

“Controlled clinical trials are now necessary to evaluate whether this method can

Research continues in an effort to determine if these neural cells can be transplanted to treat stroke, brain tumors and neurodegenerative disorders

Researchers at Cedars-Sinai’s Maxine Dunitz Neurosurgical Institute have for the first time demonstrated that stem cells from whole adult bone marrow can be differentiated into several types of cells of the central nervous system.

A long-term objective of this research is to determine if these neural stem cells can be trans

Scientists are still learning what’s in a drop of ocean water, according to this week’s Nature Magazine. And the answers have implications for the whole planet, says co-author Craig Carlson, an oceanographer at the University of California, Santa Barbara. Carlson is an assistant professor in the Department of Ecology, Evolution and Marine Biology.

About ten thousand bacterioplankton of the type SAR 11 are found in every drop of seawater. And yet, as explained in the article, which

Last April Swedish scientists discovered high levels of a potentially cancer-causing chemical called acrylamide in wide range of starch-containing foods that are fried or baked, particularly french fries, potato chips and crackers. The announcement received worldwide publicity. But at the time, no one knew where the acrylamide came from, how it was formed, or, indeed, if there is a link between acrylamide in food and cancer. The findings were quickly confirmed by the British Food Standards Agency. Ea

A broad group of discoveries about the biological powers of “small-RNA” molecules, some of which were made by researchers at Oregon State University, will be hailed on Friday as the scientific “Breakthrough of the Year” by the journal Science. Science is published by the American Association for the Advancement of Science, the world’s largest general scientific society, and each year the prestigious journal identifies what it believes were the top 10 research advances of the year.

For 2

Researchers at Washington University School of Medicine in St. Louis have discovered a possible new mechanism for regulating large groups of genes. While conducting yeast research on a potential new anticancer drug, the team identified a mechanism that enables the genome to silence large numbers of genes simultaneously, rather than each gene individually.

The finding emerged during research studying the molecular action of the drug rapamycin. Rapamycin currently is used to suppress the immu

In a significant scientific advance, researchers at the Department of Energy’s Pacific Northwest National Laboratory have identified or confirmed 490 proteins in human blood serum — nearly doubling the number of known serum proteins, according to a paper accepted for publication in the December issue of Molecular and Cellular Proteomics.

“We have performed the most extensive identification of proteins in serum to date,” said Joel Pounds, corresponding author and a PNNL staff scientist. “We s

Two scientists at The Scripps Research Institute (TSRI), Research Associate John S. Reader, D.Phil, and Professor Gerald F. Joyce, M.D., Ph.D., both of the institute’s Department of Molecular Biology, have succeeded in creating an enzyme based on a “binary” genetic code–one containing only two different subunits.

This research, described in the latest issue of the journal Nature, demonstrates that Darwinian evolution can occur in a genetic system with only two bases, and it also suppo