New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Both sides of the brain play a role in processing emotional communication, with the right side stepping in when we focus not on the “what” of an emotional message but rather on how it feels.
By studying blood flow velocity to each side of the brain, Belgian psychologists have opened a window onto the richness and complexity of human emotional communication. Their research appears in the January 2003 issue of Neuropsychology, published by the American Psychological Association (APA).
A Mayo Clinic investigation of Interleukin-6, a hormone inside cells often considered a “bad actor” of the immune system because of its association with inflammation injuries and malignant diseases, shows that it also plays a therapeutic role in mice: it protects brain cells.
Interleukin-6 — called IL-6 for short by researchers — may, in fact, be a “white knight” for mouse brain cells, or neurons, as brain cells also are called. These results, while early, may be promising for humans as w
Researchers are reporting progress in understanding whether a second light-sensing pathway in mammals indeed contributes to the detection of ambient light for controlling body functions.
In an article published in the January 10, 2003, issue of the journal Science, the researchers report that the molecule melanopsin is necessary in order for the pupil to constrict properly in response to light, a function termed the pupillary light reflex.
The latest findings by Howard Hughes Medi
Eating your own brain may not sound like a sensible approach to prolonging your life, but researchers at the University of Rochester have discovered that some single-celled organisms essentially do just that to keep themselves healthy. The findings are published in this months issue of Molecular Biology of the Cell.
David Goldfarb, professor of biology at the University of Rochester, studied the yeast Saccharomyces cerevisiae and found that contrary to what biologists have believed, th
Local fisheries part of bigger cycle affecting entire Pacific Ocean
In the late 1930s, Californias sardines supported the biggest fishery in the western hemisphere, with more than half a million tons of fish caught each year. By the mid-1950s, the sardines had virtually disappeared. Although fishing pressure may have played a part in this process, new research published in the current issue of Science indicates that the sardines demise was part of a 50-year cycle tha
The secret to its strength is a ring, Weizmann Institute researchers report in Science
Weizmann Institute scientists have found what makes the bacterium Deinococcus radiodurans the most radiation-resistant organism in the world: The microbe’s DNA is packed tightly into a ring. The findings, published in the January 10 issue of Science, solve a mystery that has long engaged the scientific community.
The red bacterium can withstand 1.5 million rads – a thousand times more tha
A University at Buffalo chemist has developed a new, high-throughput method for obtaining nuclear magnetic resonance (NMR) data that not only has the distinction of potentially performing orders of magnitude faster than conventional methods, but does so more cheaply and with greater precision.
The new method, described in the current online issue of the Journal of the American Chemical Society, has the potential to increase greatly the use of high-throughput NMR to determine protein structu
The use of hip protectors in nursing homes can reduce hip fractures by about 40%, yet acceptance of hip protectors is poor, according to a study in this week’s BMJ.
Researchers in Germany identified 42 nursing homes in Hamburg. Homes were allocated either to usual care (control group) or an intervention programme consisting of structured education of staff, who then taught residents, and provision of free hip protectors (intervention group).
Over a period of 14 months, there were 21 hip
Discovery could explain why light keeps us awake and may lead to new treatments for disorders such as jet-lag and SAD.
Researchers from Imperial College London, Johns Hopkins University, USA and Brown University, USA have discovered that melanopsin, a recently identified protein, plays a key role in a completely new light detection system in the eye.
Professor Russell Foster, from Imperial College London at the Charing Cross Hospital comments: “It had long been assumed that
Further underscoring the limitations of cholesterol screening in assessing a patient’s risk for heart disease, a new study by UC Davis physicians is the first to conclusively link C-reactive proteins (CRP) to formation of blood clots, a major cause of heart attacks, strokes and other vascular disease. Until now, CRP had been recognized mainly as a risk marker of heart disease. The study appears in the Jan. 25 print edition of the journal Circulation, a publication of the American Heart Association,
In an unusual disease known as Bloom syndrome, patients exhibit an extremely high incidence of cancers in many tissues. In fact, some experts consider Bloom syndrome to be among the most cancer-prone hereditary diseases known.
Although the illness is rare, it fascinates scientists since it can teach them more about how cancers arise and how the body normally suppresses them. Information gleaned from studies of the syndrome should provide insights into other forms of cancer, they say.
Incidents of heart attack and stroke, some fatal, in a small number of men taking the drug Viagra have remained a puzzle. After all, Viagra, commonly prescribed for erectile dysfunction, was originally developed to prevent these conditions — not only by dilating blood vessels but also by stopping platelets in the blood from clumping.
In fact, the drug does just the opposite, according to researchers at the University of Illinois at Chicago College of Medicine. They found that Viagra, by el
A potent clot-busting substance originally extracted from the saliva of vampire bats may be used up to three times longer than the current stroke treatment window – without increasing the risk for additional brain damage, according to research reported in todays rapid access issue of Stroke: Journal of the American Heart Association.
The vampire bat saliva-derived clot buster is called Desmodus rotundus salivary plasminogen activator (DSPA) or desmoteplase. DSPA targets and destroys fi
University of Georgia researchers studying rice genomes under a National Science Foundation Plant Genome Research Program award have identified the species first active DNA transposons, or “jumping genes.” The research is published in the Jan. 9 edition of the journal Nature. In collaboration with researchers from Cornell, Washington University and Japan, geneticist Susan Wessler also discovered the first active “miniature inverted-repeat transposable element,” or “MITE,” of a
In three separate studies, scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that it is possible to correct defective molecular splicing pathways that would otherwise contribute to cancer, genetic diseases and possibly other disorders.
These corrections were accomplished by the insertion into the cell of antisense oligonucleotides, short strands of genetic material that target portions of RNA. RNA carries the DNA blueprint for cellular protein produ
A 12-year study of 38,077 male health professionals found that men who drank alcohol three or more days per week had a reduced risk of heart attack compared with men who drank less frequently. Men who drank less than one drink a day had similar risk reduction to those who drank three.
Many epidemiologic studies have reported that moderate drinking–for men two drinks a day–is associated with a reduced risk of heart disease. This study looked at the relationship between quantity and frequen