New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
In the mouse model, a decrease not only in tumour growth but also a reduction in tumour volume to around one-third was observed for the first time. In the…
Familial combined hyperlipidemia is caused by the gene USF1, which in turn regulates many other genes, but until now there have been no techniques for finding…
The findings will be published in the Feb. 15 issue of Development. In this work, the team used gain- and loss-of-function mutations in mice to isolate novel…
Just a few weeks ago, teams from Bochum, Illinois, and Nevada were able to prove with terahertz (THz) spectroscopy that proteins do modify water molecules in…
But precisely how this natural protein works its magic on the cells of the immune system is not well understood. Now, however, in research that may have…
Currently, lysosomal storage diseases are treated by enzyme replacement therapy. This can be challenging because the enzyme has to find its proper way into…
The bio-crude oil can be used to produce high value chemicals and biofuels, including both petrol and diesel replacement fuels.“By making changes to the…
The work, which was posted to the Web site of the journal Nature Medicine yesterday, is a follow-up to the team’s 2006 discovery of the cellular cause of TCS. The team evaluated how a mutated TCOF1 gene causes the death of neural crest cells that should otherwise form most of the bone, cartilage, and connective tissue that make up the head and face during embryonic development. The loss of these cells results in abnormal development of the ear, nose, and upper and lower jaw, including cleft palate. …
“The practical benefit of this finding is that we can now search for new ways to lower cholesterol by designing targeted antibodies to disrupt this…
Researchers at Washington University in St. Louis and Arizona State University have sequenced the genome of a rare bacterium that harvests light energy by…
Now, Rockefeller University’s Paul Greengard and colleagues at the Karolinska Institute in Sweden provide evidence that serotonin, a well-studied…
The study, conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences and Cellular and Molecular Medicine and member of the…
The study, led by Larry R. Squire, Ph.D., professor of psychiatry, neurosciences and psychology at UCSD School of Medicine and research career scientist at the…
A pair of researchers has answered a puzzle about why efforts to lower the transmission of dengue virus in Thailand have not resulted in decreases in the…
An antiretroviral drug already in widespread use in the developing world to prevent the transmission of HIV from infected mothers to their newborns during…
A comprehensive, clinical nomogram tool, the Sunnybrook Prostate Cancer Risk Calculator – the first to use all known risk factors for prostate cancer – is…
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