New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
The probe has been developed by a team headed by Professor Ulrich Zimmermann from the Biocenter at the University of Würzburg in close mutual discussions with…
Their findings, which appear in the current issue of the journal Cancer Cell along with an independent commentary on the discovery, end a major controversy in…
“We've known it happens with females in some specialized cases, but it's probably more widespread than we ever realized before,” said Irby Lovette, the Fuller…
Their study, published this week in the early online edition of the journal Proceedings of the National Academy of Sciences, was accomplished when the…
A split-personality chemical, estrogen is thought to protect neural circuits and boost learning and memory, while at the same time increasing cancer risk when…
Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the…
The silicon-based integrated system's features could help physicians quickly arrive at the right diagnosis for timely medical intervention in patients…
The 2009 H1N1 influenza virus used a new strategy to cross from birds into humans, a warning that it has more than one trick up its sleeve to jump the species…
Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Ebola virus, which, though rare, is one of the…
A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of…
Stem cell derived neurons may allow scientists to determine whether breakdowns in the transport of proteins, lipids and other materials within cells trigger…
Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor (EGFR). Lung cancer with changes in EGFR is initially treatable with a family of chemotherapeutic agents called tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib. However, patients often develop resistance to these drugs through the acquisition of additional changes or secondary mutations…
When cells experience DNA damage, they'll try to repair it. But if that fails, the damaged cells are supposed to self-destruct, a process called apoptosis. A…
In the study, Graham George and colleagues note that mercury-based fillings, also called amalgams, have been used by dentists to repair teeth for well-over a…
Cells are not static. They can transform themselves over time — but change can have dangerous implications. Benign cells, for example, can suddenly change into…
A team of scientists from The University of Alabama used worms to reel in information that they hope will lead to a greater understanding of cellular…