New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Although the tropics appear to the casual observer to be busily buzzing and blooming with life's rich variety when compared with temperate and polar regions—a…
Galactosemia is a metabolic disease resulting from an inherited defect that prevents the proper metabolism of galactose, a sugar commonly found in dairy products, like milk. Exposure of affected people to galactose, can damage most of their organ systems and can be fatal. The ability to study the disease is limited by a lack of animal models. New information suggests that similarities between humans and flies may provide scientists with useful clues. The inability to breakdown simple sugars in common…
“There's a whole world beyond SNPs — single nucleotide polymorphisms — and we've stepped into that world,” says Brian Teague, a doctoral student in genetics at…
In its latest Perspectives in General Physiology series, the Journal of General Physiology (JGP) offers an in-depth look at several of these methods and the…
When the first warm rays of springtime sunshine trigger a burst of new plant growth, it's almost as if someone flicked a switch to turn on the greenery and…
Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and…
Researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley, have…
“Over the past decade, we have evaluated numerous therapeutic approaches for the treatment of lethal viruses, such as Ebola,” said co-author Dr. Lisa E….
The theoretical structure was confirmed via comparison to experimental results obtained by X-ray diffraction from powder samples of the pure cluster material….
Apelin is a recently discovered peptide that binds to the apelin (or APJ) G-protein-coupled receptor. Apelin-13 (NH2-QRPRLSHKGPMPF-COOH), one of several…
Tonsillectomy is among the oldest and most commonly performed procedures in the pediatric population. Approximately 530,000 outpatient pediatric…
A compound found in sunless tanning spray may help to heal wounds following surgery, according to new results published by plastic surgeons from…
A team of scientists from government, academia and private industry has developed a novel treatment that protects mice from infection with the bacterium that…
In human babies, a defective maternal Ube3a gene causes a developmental condition known as Angelman syndrome that leads to mental retardation, speech…
The work, co-led by geneticists at the UCSD Institute for Genomic Medicine, together with colleagues from institutes and universities in Paris, Rome and…
High-resolution nuclear magnetic resonance (NMR) spectrometry is one of the most powerful analytical tools for the precise determination of molecular…