Persilastaffanes are an unusual new class of compounds that are introduced in the journal Angewandte Chemie by Japanese researchers led by Takeaki Iwamoto at…
Much of what living cells do is carried out by “molecular machines” – physical complexes of specialized proteins working together to carry out some biological…
The findings will be published online January 8 in the journal Nature Chemical Biology. MPS is caused by the absence or malfunctioning of a lysosomal enzyme…
The team, from the University of Cambridge and the Medical Research Council (MRC) Toxicology Unit at the University of Leicester, publish their findings today…
A tiny, freshwater flatworm found in ponds and rivers around the world that has long intrigued scientists for its remarkable ability to regenerate has now…
Viral diseases are still one of the biggest challenges to medical science. Thanks to thousands of years of co-evolution with humans, their ability to harness…
As DMD patients age, their damaged muscle cells are gradually replaced by collagen-rich, fibrous tissue. This muscle fibrosis is partly induced by the growth…
Countless mice, rats and rabbits die every year in the name of science – and the situation is getting worse.While German laboratories used some 2.41 million…
Prof. Irit Sagi of the Biological Regulation Department and her research group have spent years looking for ways to home in on and block members of the matrix…
When investigating new potential therapies, scientists are often confronted with an experimental problem: Neurons are embedded deep into the tissue of the…
Oxidative stress is the cause of many serious diseases such as cancer, Alzheimer’s, arteriosclerosis and diabetes. It occurs when the body is exposed to…
Conservation of angular momentum is a fundamental property of nature, one that astronomers use to detect the presence of satellites circling distant planets….
Cancer cells' sugar cravings arise partly because they turn off their mitochondria, power sources that burn glucose efficiently, in favor of a more inefficient…
An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of…
The compound — delta-12-protaglandin J3, or D12-PGJ3 — targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice, said Sandeep…
HHMI researcher Ronald Breaker of Yale University has discovered the cellular chain of events that occurs inside a bacterium after it encounters fluoride in…
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