The recombinant TLR-MD-2 fusion protein or a fusion protein homopolymer / heteropolymer complex can be used for the prophylactic and/or therapeutic treatment…
The invention relates to a method for monitoring the expression level of a gene in a host by modulating the activity of a regulatory biomolecule. The…
The invention describes a method to identify T-cells (CTL, CD4+ T-helper), which are specifically directed to or have a highly specific cross-reactivity with…
A new receptor-dead BMP-2 mutein L51P has been created that has no detectable BMP activity. Surprisingly, the BMP-2 L51P mutein exhibits an unaltered binding…
The invention discloses a MCSP epitope recognized by CD4+ T lymphocytes. MCSP-specific T-cell clones from the peripheral blood of a healthy human donor could…
The invention provides a new polymer bioceramic and bioresorbable composition suitable as filler, wax and glue. The polymer composition can be used in bone…
The invention relates to an insertion element, wherein the element is a recombinant DNA molecule comprising recombinase binding sites, a resistance gene and a…
A public-private effort to develop more fuel-efficient automobiles and eventually introduce hydrogen as a transportation fuel is well-planned and identifies all major hurdles the program will face, says a new report from the National Academies’ National Research Council. Many technical barriers must be overcome and new inventions will be needed, but the program, which was launched three years ago, has already made an excellent start, said the committee that wrote the report.
California fiddler crabs may be among the world’s pickiest animal when it comes to selecting a mate.
A study conducted by a biologist at the University of California, San Diego that appears in the August issue of the journal Animal Behaviour found that females of the species Uca crenulata may check out 100 or more male fiddler crabs and their burrows before finally deciding on a mate.
“As far as I know, no other species has been observed sampling nearly as many cand
Visceral leishmaniasis, which is the most severe form of that group of diseases, affects 500 000 people in the world each year. It is caused by a protozoan, Leishmania infantum, transmitted by sand fly bites. There is no vaccine for this disease, which can rapidly lead to death if no treatment is given. In the most heavily affected areas, the dog population is hit heavily by infection. It acts as parasite reservoir for humans.
Development of a vaccine for dogs could help brake transmission
In an unusual collaboration among scientists and humanists, a Cornell University team has demonstrated a novel method for recovering faded text on ancient stone by zapping and mapping 2,000-year-old inscriptions using X-ray fluorescence (XRF) imaging.
The research, carried out at the Cornell High Energy Synchrotron Source (CHESS), applies a nondestructive chemical analysis technique widely used in geology, archaeology and materials science.
“X-ray fluorescence imaging h
First treatment for incurable disease comes into focus
University of Florida scientists used a healthy human gene to prevent blindness in mice with a form of an incurable eye disease that strikes boys.
Writing in the August issue of Molecular Therapy, scientists from the UF Genetics Institute describe how they successfully used gene therapy in mice to treat retinoschisis, a rare genetic disorder that is passed from mothers, who retain their sight, to their sons.
Multi-institutional study addresses critical GVHD complication
Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors. The study was designed to determine whether one of two general approaches to prevent graft-versus-host-disease (GVHD), a potentially lethal complication, might result in improved survival.
’Orbitronics’ could keep silicon-based computing going after today’s technology reaches its limits
For about 40 years, the semiconductor industry has been able to continually shrink the electronic components on silicon chips, packing ever more performance into computers. Now, fundamental physical limits to current technology have the industry scouring the research world for an alternative. In a paper published in the Aug. 1 online edition of Physical Review Letters
After reviewing new sound recordings from the White River of Arkansas, an independent team of ornithologists has confirmed the existence of the Ivory-billed Woodpecker.
Working from previously unpublished data provided to them in the last few days by John Fitzpatrick and colleagues at Cornell University, ornithologists at Yale, the University of Kansas, and Florida Gulf Coast University have concluded that the bird has been indeed been detected for the first time in decades.
Researchers at Case Western Reserve University School of Medicine and the Ireland Cancer Center of University Hospitals of Cleveland report identifying a new DNA gene marker, vimentin, that was shown in a recent study to be three times more effective in detecting colon cancer than the standard doctor’s office test that detects blood in the stool. The study, appearing in the August 3, 2005 issue of the Journal of the National Cancer Institute, was conducted by a team also comprised of research
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