– a step towards more sustainable superconductor applications. The study by Politecnico di Milano, Chalmers University of Technology, and Sapienza University of Rome, published in Nature Communications. Taking a significant step forward in superconductivity research, the discovery could pave the way for sustainable technologies and contribute to a more environmentally friendly future. The study just published in Nature Communications by researchers from Politecnico di Milano, Chalmers University of Technology in Göteborg and Sapienza University of Rome sheds light on one…
Scientists are developing an experiment to test whether gravity is quantum – one of the deepest questions about our universe. Scientists are developing an experiment to test whether gravity is quantum In quantum mechanics, which describes the behaviour of atoms and molecules –objects behave differently to everything we know: they can be in a quantum superposition of being in two places at the same time Now, scientists are investigating a way to determine whether gravity operates in this way, by…
– and how to cure it. Research demonstrates how the genetic defect causing this rare, congenital disease could be repaired through CRISPR. University at Buffalo research has identified how a misstep in the genesis of a key component of the kidney causes infantile cystinosis, a rare disease that significantly shortens the lifespan of patients. Published Nov. 30 in the International Journal of Molecular Sciences, the work reveals that the mechanisms that cause the disease could be addressed and potentially cured through…
Like a shiny, round ornament ready to be placed in the perfect spot on a holiday tree, supernova remnant Cassiopeia A (Cas A) gleams in a new image from NASA’s James Webb Space Telescope. As part of the 2023 Holidays at the White House, First Lady of the United States Dr. Jill Biden debuted the first-ever White House Advent Calendar. To showcase the “Magic, Wonder, and Joy” of the holiday season, Dr. Biden and NASA are celebrating with this new image…
…demonstrate efficacy without neurotoxicity in B-cell lymphoma phase 1 clinical trial. The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm. Anti-CD19 CAR T-cells with a CD28 co-stimulatory domain, such as axicabtagene ciloleucel and brexucabtagene autoleucel,…
The ‘burrowing effect’ of foraminifera on marine environments. Impact of single-cell organisms on sediment oxygen levels and bacterial diversity measured for the first time. Dr. Dewi Langlet, a scientist at the Evolution, Cell Biology and Symbiosis Unit at the Okinawa Institute of Science and Technology (OIST), studies foraminifera, single-cell organisms with shells made of calcium carbonate. He and his collaborators have shown for the first time that the burrowing of single-celled organisms in marine ecosystems affects oxygen distribution and bacterial diversity in…
Researchers develop novel cancer protein killer and discover a new ligase for PROTACs. Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical research. They mark proteins for targeted degradation by the cell’s own protein disposal system. The research groups led by Herbert Waldmann from the Max Planck Institute…
…enable Faster Migration Analysis of Immune Cells. Immune cells fight infectious intruders, for example, or search for incipient cancers. Therefor, they are constantly migrating through the tissues of our body. But in the wrong place, immune cells like neutrophil granulocytes can cause damage: If these white blood cells infiltrate tumours, this is often associated with a poor prognosis for patients. This is why they could benefit from drugs that prevent neutrophils from migrating into tumours. Until now, this migration has…
EPFL researchers have developed a hybrid device that significantly improves existing, ubiquitous laser technology. EPFL researchers have developed a hybrid device that significantly improves existing, ubiquitous laser technology. The team at EPFL’s Photonic Systems Laboratory (PHOSL) has developed a chip-scale laser source that enhances the performance of semiconductor lasers while enabling the generation of shorter wavelengths. This pioneering work, led by Professor Camille Brès and postdoctoral researcher Marco Clementi from EPFL’s School of Engineering represents a significant advance in the…
Researchers from Helmholtz Munich and the LMU have discovered that, in the case of brain injuries, specific cells in the brain become active in disease situations, exhibiting properties of neural stem cells. The authors further discovered that a specific protein regulates these cells and hence could function as a target for therapy and thereby contribute to better treatments for brain injuries in the future. The new findings shed light on the specificity of astrocyte reaction in different injury conditions and…
Drexel University’s ‘BioFiber’ can stabilize and heal damaged concrete. In hopes of producing concrete structures that can repair their cracks, researchers from Drexel University’s College of Engineering are putting a new twist on an old trick for improving the durability of concrete. Fiber reinforcement has been around since the first masons were mixing horsehair into their mud. But the Drexel research team is taking this method to the next level by turning reinforcing fibers into a living tissue system that…
Unveiling CO2 absorption dynamics. Magnesium oxide is a promising material for capturing carbon dioxide directly from the atmosphere and injecting it deep underground to limit the effects of climate change. But making the method economical will require discovering the speed at which carbon dioxide is absorbed and how environmental conditions affect the chemical reactions involved. Scientists at the Department of Energy’s Oak Ridge National Laboratory analyzed a set of magnesium oxide crystal samples exposed to the atmosphere for decades, and another for…
Janelia researchers unveil comprehensive collection of rhodamine-based fluorescent dyes. When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn’t know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a thing or two about medicinal chemistry. On a whim, Grimm and Janelia Senior Group Leader Luke Lavis decided to try using a mainstay medicinal chemistry reaction Grimm had picked up in the pharmaceutical industry…
…unlock new potential for brain science. Goggles enabled researchers to study responses to overhead threats for first time. Northwestern University researchers have developed new virtual reality (VR) goggles for mice. Besides just being cute, these miniature goggles provide more immersive experiences for mice living in laboratory settings. By more faithfully simulating natural environments, the researchers can more accurately and precisely study the neural circuitry that underlies behavior. Compared to current state-of-the-art systems, which simply surround mice with computer or projection…
When we last checked in with Caltech’s Kerry Vahala three years ago, his lab had recently reported the development of a new optical device called a turnkey frequency microcomb that has applications in digital communications, precision time keeping, spectroscopy, and even astronomy. This device, fabricated on a silicon wafer, takes input laser light of one frequency and converts it into an evenly spaced set of many distinct frequencies that form a train of pulses whose length can be as short…
A navigation belt helps visually impaired people to reach their destination. You enter the route you want to take via an app, press “start” and the belt guides you in the right direction like a compass. The German Institutes of Textile and Fiber Research Denkendorf (DITF) have developed a contacting process with which this orientation aid – and e-textiles in general – can be produced more economically and conveniently. When you have to turn into a street, the naviBelt® from…