At present about 18 million people worldwide suffer from Alzheimer disease, a neurodegenerative disorder which leads to dementia. The pharmaceuticals currently registered for the treatment of Alzheimer are only able to reduce symptoms marginally and delay progression of Alzheimer disease to a limited extent. The novel preventive target structure, the APP-AICD/ Fe65-PTB2 complex, offers a new chance for the development of a possible pharmaceutical for a causal treatment of Alzheimer disease.
Researchers at the Karlsruhe Institute of Technology (KIT) have successfully developed low-cost, fluorescent dyes with especially high light intensities. These inorganic–organic hybrid dyes can be synthesized easily and isolated, stored and redispersed in common solvents (ethanol/water). They can be excited using blue light (UV or blue light from LED) and emit depending on their composition in the blue, green, red or infrared spectrum. Preferred are applications in the field of medical diagnostic and therapeutic, advertising material and safety equipment (fluorescent marker).
We present a novel network design for high-performance computing (HPC). Our network architecture provides a scalable, low-cost, and power-efficient network with very high bandwidth and low latency.
Customer for the 596 Megawatt (MWe) plant in Płock is PKN Orlen, Eastern Europe's largest mineral oil company. The plant located around 100 kilometers…
Superconductivity is a remarkable phenomenon: superconductors can transport electric current without any resistance and thus without any losses whatsoever. It…
A new National Science Foundation-supported project will provide computational tools designed to help identify and characterize the gene diversity of the…
In a paper scheduled for online publication in the Proceedings of the National Academy of Sciences this week, University of Michigan researchers and their…
But the primary reason to expend so much effort on this area boils down to one fact: The rate of uplift is among the highest ever observed by satellite…
Knowing properties of materials at different temperatures is important in engineering, said Gregory McKenna, a professor of chemical engineering and the John…
While “island tameness” is an old idea, there have been few rigorous studies of the phenomenon. Many aspects remain unclear, including the mechanisms behind it…
Researchers at the Max Planck Institute of Biochemistry in Martinsried near Munich have recently uncovered a previously unknown mechanism explaining how this…
The Joint Science Conference (GWK) of the federal and state governments has ratified the 2015 Academies' Program, coordinated by the Union of the German…
They are one of the great hopes for target-oriented treatment approaches: the so-called small interfering RNA-molecules, siRNA. These are able to mute specific…
The glaciers in the Amundsen Sea Embayment in West Antarctica are hemorrhaging ice faster than any other part of Antarctica and are the most significant…
The new study focused on the meniscus, a wedge-shaped piece of cartilage in the knee that acts as a shock absorber between the femur, or thighbone, and tibia,…
“Chest X-rays can be a valuable exam when ordered for the correct indications,” said Ann Packard, M.D., radiologist at the Mayo Clinic in Rochester, Minn….
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