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Oligonucleotide Mixture for Detecting Cell Culture Contaminants

Since cell culture contamination cannot be totally avoided, regular testing is a key factor for good cell culture management. The present invention provides…

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Griseofulvin Analogues: Targeting Cancer Through Centrosomal Inhibition

DKFZ together with Technical University of Denmark (DTU) developed an analogue of Griseofulvin as a compound for cancer treatment, which selectively targets…

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Quadscanner: Fast, Adaptive Optical Scanning Device

Quadscanner for High Resolution Scanning Microscopes. The key facts are: (1) Fast, adaptive optical scanning device; (2) Completely free positioning of the…

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Hyaluronic Acid and Cytokines: New Hope for Osteoarthritis

Background

The intraarticular injection of hyaluronic acid (HA) in patients with osteoarthri-tis is so far the most promising treatment…

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Mesoporous Metal Oxide Films: Enhancing Industrial Processes

Background

Many industrial processes rely on metal oxides with high surface area. Thin porous metal oxide films offer unique physical,…

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Innovative Methods to Inhibit IL-4 and IL-13 Signaling

The current patent application deals with the inhibition of signalling through the cytokines IL-4 and IL-13. Pathologically increased activation of this…

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Innovative Biomarkers Enhance Prognosis in Pancreatic Cancer

This invention affects methods and means for the prognosis of survival time in pancreatic cancer patients, particularly in pancreatic ductal adenocarcinoma.

It is based on a developed expression matrix of genes which is then used to deduct the survival time of pancreatic cancer patients using a newly developed bioinformatics algorithm.

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Detecting TGF-Beta Receptor Activation: New Reporter Construct

Molecules involved in signal transduction of TGF-beta family such as TGF-beta, Activin, or Bone Morphogenetic Proteins (BMPs) have important function in many…

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Enhancing Cartilage Assessment with Ultrasound Palpation System

Background

The cartilage quality (thickness and stiffness) is commonly determined either visually or by manual palpation. Both procedures…

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Innovative Method for Installing Offshore Foundations Efficiently

Background

It is still a main problem in the offshore industry to install foundations that satisfy the acoustic limiting values set by…

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Protein biomarker set for personalized treatment of ERα-positive breast cancer

Breast cancer has been recognized as a heterogeneous

disease that consists of different intrinsic

subtypes, including hormone receptor positive

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CO2 Capture – Gas Treatment with Lipophilic Amines

An innovative method for the separation of CO2 from gases, e.g. flue or synthesis gas, by chemisorption using an aqueous solution of mixed lipophilic amines,…

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ULTRAPORCRETE – High Strength Porous Concrete

UPC is a high strength, chemically swelled, air curing

and mineral-binding Construction-Concrete. UPC shows a high mechanical load capacity and is at the…

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CorA as anthelmintic – Natural product as antibiotic for the treatment of filariasis

Human filariasis (elephantiasis and river blindness) is caused by the nematodes W. bancrofti and O. volvulus, transmitted via blood sucking insects. The worms…

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CorA as anthelmintic – Natural product as antibiotic for the treatment of dirofilariasis

Dirofilariasis is caused by Dirofilaria immitis and D. repens, parasitic nematodes, which are transmitted by blood sucking mosquitoes. The heartworms harbour…

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Biocompatible Bone Substitute: Advancements in Tissue Engineering

Background

Bone medicine and tissue engineering is becoming increasingly important in the ageing modern society. Up to 55% of over fifty…

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Unlocking Diagnosis: The Power of Ultrasound Elastography

Background

Elastography has recently emerged for diagnosing pathologies based on variations in tissue stiffness. Due to its high…

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New Techniques Enhance Retroviral Vector Production for Gene Therapy

Technology

Based on high-level secondary research, current production systems allow for titers of ~106 – 108 functional virus particles…

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New Recombinant Production of Design Rhamnolipids – Optimized Biosurfactant Fermentation Process

Biosurfactants have attracted increasing interest since they show a number of advantages over surfactants of petrochemical origin in terms of ecological…

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Exploring White Light Emission Innovations in LED Technology

Background

White light emission with LEDs is achieved today by either mixing red, green and blue (RGB) LEDs or by covering monochromatic…

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