Scientists of Saarland University have recently succeeded in developing an improved series of new non-steroidal inhibitors of 17b-HSD2. Since 17b-HSD2 is…
Scientists of Saarland University have recently succeeded in developing the first CYP11B1 inhibitors showing good selectivity. As starting point the highly…
Scientists of Saarland University have developed a setup, which allows a controlled manipulation of cells via cell‐surface‐interaction. Therefore biocompatible…
Most quinones, with coenzyme Q10 as their best known representative, are seen as very efficient radical scavengers and antioxidants, commonly acting in a way…
Many fluorescent dyes are based upon chromophores with a highly delocalised pi-system. Especially functional rylene type dyes are of great technical importance…
The natural product etnangien represents a new structural type of a particularly efficient RNA polymerase inhibitor. It is effective against a broad panel of…
At Saarland University, a procedure has been developed that allows a significant enhancement of water solubility of photosensitizers of the porphyrin and…
Background
There is still a considerable demand for the improvement of cytotoxic cancer
…
Background
For the prognosis of the flavor stability of beer the electron spin resonance (ESR) spectroscopy has been used for the…
Background
Cytokinins are plant hormones involved in cell division, shoot meristem and leaf formation, chloroplast biogenesis, and…
Background
LINE-1 (Long INterspersed Element-1) elements represent the major class of mammalian non-LTR (long terminal repeat)…
Bckground
Interferons play a vital role in the natural response on viral infection. In particular, type I interferon (IFN-I) is the focus…
Background
Immunotoxins have to be administered in high doses due to low cytosolic
…
Background
Every second woman and eighth man over age of 50 suffers from bone fracture or defect. 20% of the patients face a serious…
Background
Rheumatic diseases are the most common chronic inflammatory disorders. Approximately 1 out of 100 humans in western…
Background
Bone cements based on polymethylmethacrylate (PMMA) are mostly used for the anchorage of artificial joints, as bone…
The treatment of paraphilias and related disorders has been challenging for patients and clinicians for a long time. The main problems of recent drug therapies…
Technology
Novel high affinity aptamers have been selected which inhibit the agonistic effect of autoantibodies specific for the second…
We offer a novel automated eight well mixing chamber that guarantees a uniform distribution of micro particles in a suspension for every single measurement….
Technology
A novel drug polymer conjugate consisting of a dendritic polyglycerine (PG) core of 3-5 or more glycerol units and a…
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