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Enhancing Material Applications with Advanced Force Sensors

For many material applications the interaction of their components on the molecular level and their correct measurement and characterization is of high…

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New Method for Parallel Detection of Protein Phosphorylation

Phosphorylation of specific amino acid residues is the most

common posttranslational modification of proteins and has

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Luminescent Coordination Polymers: New Advances Explained

This technology describes coordination polymers (MOF) consisting of alkaline earths doped with rare earth ions as luminescence centres and basic…

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Targeting CHIP: New Insights for Muscular Dystrophy Treatment

Muscular dystrophies are a heterogenous group of inherited single-gene disorders, characterized clinically by progressive muscle weakness and wasting. In…

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Discovering Reversible Cathepsin B Inhibitors for Key Health Issues

Cathepsin B is an abundant and ubiquitously expressed cysteine peptidase involved in many pathological processes, such as inflammation, parasite infection and…

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Discover New Trialkylborate Compounds for Advanced Syntheses

A new category of borate compounds enables syntheses, which are difficult to realize, like the synthesis of duroplast precursors, ceramics and metal amides.

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HLA-A2-restricted peptide epitopes of fibroblast activation protein alpha (FAPα) for cancer vaccination

The following invention is a new, peptide based vaccination against genetical stable tumor stroma-associated antigens. Because of significant upregulation of…

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Early and differential diagnosis test for Alzheimer’s disease

Alzheimer‘s disease (AD), widely regarded

as the most common cause of dementia,

is a progressive neurological disorder. It

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Innovative Plants Boost Resistance to Drought and Salt Stress

The here described invention comprises plants with increased resistance to drought or salt stress, and an increased yield. The resistance is caused by the…

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Peptide Method Enhances Gene Expression Monitoring in Host Cells

The present invention relates to a method for monitoring the expression level of a gene in a host by modulating the activity of a regulatory bio molecule. The…

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New IL-3 Blockade Strategy Shows Promise for RA Therapy

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory

disorder that attacks the joints producing an inflammatory synovitis. About 1% of the world‘s…

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Mouse Models Reveal Cacna2d2 Gene Insights for Drug Research

Cacna2d2 gene variant leading to voltage-gated calcium channels with modified properties. entla-mice show ataxia, paroxysmal dyskinesia, and epileptic…

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The potent TGF-β antagonist Norrin as a new drug for the treatment of fibrotic diseases and cancer

Human Norrin protein has been originally identified in the art as being a crucial

factor in the development of Norrie disease and is thought to be…

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Nucleoside Analogs and Inhibitors Target Epithelial Cancer Stem Cells

Epithelial cancers are among the most

frequent causes of death. Especially

pancreatic carcinomas are characterized

by early metastatic spread and…

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Unlocking Biotech Potential: Sulfolobus Shuttle Vector Insights

Sulfolobus spp., a thermoacidophilic crenarchaeote, can be easily grown in

the laboratory and is interesting from a biotechnological point of view. Due

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Boosting Plant Biomass: Carbohydrate Alterations Combat Pathogens

Carbohydrates are generated by photosynthesis in green plant cells. In higher plants

they are transported from green tissues (source tissue) to other parts…

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Innovative Antitumoral Compounds from Tropical Lianas

Plants are an important source of pharmacologically active substances. The tropical

lianas of the families Dioncophyllaceae and Ancistrocladaceae are rich in…

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Arylisoquinolines: New Agents Against Biofilm and Infections

Supply of novel, highly effective and non-toxic agents

– Improved prevention of biofilm-formation

– Treatment of infectious diseasesFurther Information: PDF Bayerische Patentallianz GmbH…

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New FRET Method Enhances Hsp90 High-Throughput Screening

The molecular chaperone heat shock protein 90 (Hsp90) couples ATP hydrolysis

to conformational changes driving a reaction cycle that is required

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New Depot System Transforms Protein Delivery with VPG Gels

The invention is a lipid based delivery systems based on a vesicular phospholipid gel (VPG) formulation comprising tightly packed liposomes. Protein…

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