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Adenosine A2A Prodrugs – Phosphorylated A2A receptor agonist prodrugs as anti-inflammatory agents with improved tolerance

A2A agonists are well known for their anti-inflammatory

action. A new class of compounds is presented that allows

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GlioMethyl – Promotor methylation of the DUSP-4 gene as predictive parameter for gliomas

Gliomas, especially secondary glioblastomas, are affected

with hypermethylation of the promoter region of the

Environmental Conservation

Scientists Refine Seawater Equation for Enhanced Ocean Research

This summer, one of the world’s leading ocean science bodies, the United Nations Educational, Scientific and Cultural Organization’s (UNESCO’s) and…

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Innovative Metal Films: Large-Scale Macroporous Solutions

The present invention permits to produce large-scale macroporous metal films and three-dimensional structures.

The simple process uses renewable raw…

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Simple Plant Vitality Monitoring: Boosting Root Oxygen Supply

The novel process permits simple and direct monitoring of plants, and in particular of the oxygen supply to their roots. Various measurements on the surfaces…

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New Actuator Design Using Electroactive Polymer Technology

The present invention is a novel principle for the use of electroactive polymers (EAPs). It is realised by a tubular device that contains the polymer. An…

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Chitinosanase – Novel chitosan-cleaving enzyme with defined specificity for the production of chitosan-oligomers

Chitosan is a linear co-polymer of glucosamine (D) and N-acetyl-glucosamine (A) units. Enzymatic degradation of this co-polymer by chitinases or chitosanases…

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Simplifying Carbohydrate Mimics Synthesis for Innovative Uses

The invention permits to synthesize easily carbohydrate-C-N and glycosamine mimics from natural carbohydrate and glycol. The synthesized molecules can be used…

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Silicon Carbide Innovation from Renewable Materials

The present invention permits to produce silicon carbide from renewable raw materials. It is particularly suitable for the synthesis of high-purity crystalline…

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Protein Aggregation Inhibitors: New Hope for Neurodegenerative Diseases

Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and prion diseases share molecular mechanisms including protein aggregation and…

Information Technology

Green500: Supercomputers’ Energy Efficiency Hits New High

“The average energy efficiency of the top supercomputers in the world increased by 10 percent,” said Wu Feng (http://people.cs.vt.edu/~feng), an associate…

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Innovative Analysis of Plasma Phosphoglycerides’ Fatty Acids

Cardiovascular diseases, cancers, immune diseases and mental development of children are related to the fatty acid composition of circulating lipids and…

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Transparent Glass Foams: Innovating UV-Absorbing Materials

The invention is a novel process for manufacturing highly optically transparent glass foams with an absorption edge in the UV range. The foams are manufactured…

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High Antiviral Activity Found in New Active Substance Fractions

Even though a number of well characterized substances and formulations with antiviral activity exist, there is still a need for new active substances….

Life & Chemistry

Hopkins scientists find cells responsible for bladder cancer's spread

Johns Hopkins scientists have tracked down a powerful set of cells in bladder tumors that seem to be primarily responsible for the cancer’s growth and spread…

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Peptide Method Enhances Gene Expression Monitoring in Host Cells

The present invention relates to a method for monitoring the expression level of a gene in a host by modulating the activity of a regulatory bio molecule. The…

Life & Chemistry

Advancements in Artificial Cells: Enhancing Cosmetic Delivery

In cosmetics, lipid vesicles, also known as liposomes, effectively transport ingredients through the skin. However, they are also used to encapsulate…

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Electromagnetic Microsystem for Magnetic Bead Manipulation

The invention describes an electromagnetic microsystem for manipulating and separating magnetic micro and nanobeads conjugated with biomolecules. Further…

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Bacterial TIR Domain Mimics: New Hope for Autoimmunity and Infections

Pathogenic microbes possess sophisticated molecular tools to suppress the immune response of their mammalian hosts. Recently, a novel mechanism used by…

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Mikro-Speckle Interferometer: Precision in Microscopic Measurement

The novel Micro-Speckle Interferometer opens a new dimension in speckle interferometry as it allows precise measurement of microscopic objects, even those with…

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