The invention discloses a MCSP epitope recognized by CD4+ T lymphocytes. MCSP-specific T-cell clones from the peripheral blood of a healthy human donor could…
A new receptor-dead BMP-2 mutein L51P has been created that has no detectable BMP activity. Surprisingly, the BMP-2 L51P mutein exhibits an unaltered binding…
The invention describes a method to identify T-cells (CTL, CD4+ T-helper), which are specifically directed to or have a highly specific cross-reactivity with…
The invention relates to a method for monitoring the expression level of a gene in a host by modulating the activity of a regulatory biomolecule. The…
The recombinant TLR-MD-2 fusion protein or a fusion protein homopolymer / heteropolymer complex can be used for the prophylactic and/or therapeutic treatment…
The novel conjugate molecules are provided for the manufacture of a medicament for gene therapy, apoptosis, or for the treatment of diseases such as cancer,…
The invention relates to a pharmaceutical composition comprising an inhibitor of SLY-1 (SH3 domain protein expressed in lymphocytes).Further Information: PDF Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V….
The invention consists of a new system for the expression of proteins in E. coli and its applications.
Compared to the state of the art the new autodisplay…
This invention covers a new process that allows the stabilization and activation of sensitive catalysts (respectively enzymes) to be used in organic…
The invention concerns a market ready and provable technical process for the “super activation” of polysaccharides (e.g. cellulose, starch, chitin) for the…
The invention affects the novel bacterial enzyme 1,5-anhydro-D-fructose-reductase. In a regio- and stereoselective reaction 1,5-anhydro-D-fructose (AF) is…
Since the discovery that short double-strand RNA molecules (siRNAs) can trigger sequence-specific degradation of target RNA in cells, great efforts are going…
Normally the measuring device of a force sensor is made of one piece of high-quality spring steel. Afterwards strain gauges are pasted on the device or the…
Today's graphics hardware is very fast but realism can only be achieved by manually tweaking and approximating lighting and visual effects such as reflections…
A multifunctional graft for use in vascular surgery: The principle is based on surface modification and drug elution out of a silicone coated polyester…
The new target named TEC1 is essential for the virulence of C. albicans. It suppresses the fungicidal functions of macrophages and is required for the evasion…
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