Professor Ritter and his co-workers from the Division of Virology, University Hospital of the RWTH Aachen, created a new recombinant Epstein-Barr Virus (EBV)
which has lost the ability to enter the state of latent persistency after infecting host cells. The mutant virus only causes a self-limited infection and is unable to immortalize B-lymphocytes following Infection. Having lost the oncogenic potential of wild type EBV it fulfils the prerequisite for a live vaccine.
The inventors generated a mutant virus allowing expression of lytic genes, but preventing the expression of EBV encoded genes essential for the establishment of
viral latency. Mutant virus infected B-lymphocytes died after the productive phase….
Protective natural products from sessile animals as highly efficient bioactive antifouling agents.
BIANTS are synthesised bastadins, modified depsipeptides,…
Purinergic receptors have been in the focus of drug discovery for many years. This invention provides nonnucleotide
agonists of the P2Y11-receptor. The…
New peptides for the prevention and treatment of atherosclerosis
Further Information: PDF PROvendis GmbHPhone: +49 (0)208/94105 0ContactDipl.-Ing. Alfred…
A novel fermentation method for fed-batch operating
conditions, based on microtiterplates (MTPs) was developed at the Dept. of Biochemical Engineering, RWTH…
Invention
The therapeutic use of dendritic cells in vaccination approaches requires prior activation of these immune cells. The invention exploits the power…
Scientists at the University of Cologne have developed a new inducible expression system, which is easy to use, reliable and very fast. The System is based on…
The miniaturized intraoral ultrasound scanner enables the
precise measurement of the geometry of prepared teeth.
…
In terms of process technology, the transport and the
enrichment of liquids with other substances or gases
…
The exact determination of the mechanical leg axis is
crucial for successful Total Knee Arthroplasty (TKA) . A
…
Neurosurgeons at the University Hospital of the RWTH Aachen have developed a new holder for trocars which are used within microsurgical procedures of the…
Scientists at the University of Cologne, Germany, have linked successfully a trans-membrane ATPase to the hereditary parkinsonism Kufor Rakeb syndrome PARK9….
Invention
The Chair of Biochemical Engineering at RWTH Aachen
…
Scientists at the University of Bonn have identified new small molecules which can be used for the treatment of diseases characterized by alterations of…
A novel ex vivo method for immediate early diagnosis and prognosis of proliferative diabetic retinopathy (DRP) is provided with DRPevader.
DRPevader is based…
Scientists at the University of Bonn, Germany, have identified the main target antigen for the atypical antineutrophil
cytoplasmic antibodies pANCA in…
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