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Identifizierung Relevanter Gene Für Die Metastasierung

Aktuelle Prognosen gehen davon aus, dass der Krebs bereits im Jahr 2010 Herz-Kreislauf-Erkrankungen als Haupttodesursache ablösen wird. Nach Schätzungen treten…

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…Nucleic acid delivery

Die Gentherapie umfasst eine Vielfalt biomedizinischer Anwendungen und liefert zahlreiche Methoden, um schwere Krankheiten wie z.B. Krebs zu behandeln. Sie…

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Trinukleotidsynthos: Effiziente Methoden Für Gezielte Mutagenese

Im letzten Jahrzehnt hat das Interesse an effizienten Methoden für die gezielte Mutagenese stark zugenommen. Dabei stehen die Funktionsoptimierung von…

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Innovative Festphasensynthese Für Trinukleotide Erforscht

Alle bisherigen bekannten Verfahren zur Synthese von Trinukleotidsynthons verlaufen in der

Lösungschemie nach dem Phosphortriesterverfahren oder dem…

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Single-Chamber Electrophoresis: A New Approach to Analysis

The new Electrophoresis System allows the analytic separation of proteins and nucleic acids and the following production of purified molecule groups without…

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Targeted Retrieval of Recombinase Activity via Trans-Splicing

The Cre/lox system constitutes a method for the site-directed recombination of nucleic acids, in which the enzyme Cre-recombinase achieves recombination of DNA…

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Enhancing Precision: The Role of Parting and Grooving Tools

High precision tooling is the cornerstone of mechanical engineering enabling faster and more accurate production of machines and components for all the…

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Heparin Nitroxide Derivatives: Enhanced Antioxidant Properties

Heparin Nitroxide Derivatives possess antioxidant and paramagnetic properties and perform the role of a scavenging agent . Therefore they are applicable to the…

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New Species-Independent Method for Detecting Biological Material

The SAPD-PCR (Specific amplified polymorphic DNA-PCR) is a species-independent detection method that allows the determination of the genetic relationship of…

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Exploring Benzoquinone-Based Antioxidants for Better Health

Most quinones, with coenzyme Q10 as their best known representative, are seen as very efficient radical scavengers and antioxidants, commonly acting in a way…

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Innovative Organic Recovery After Whole Cell Biotransformation

In the method according to the invention the culture medium is added olafluor and/or stannous fluoride at the end of the cultivation time. The bioemulsifiers…

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Innovative Therapy Strategies for Lung Melanoma and Asthma

Patients with metastasized melanomas have a poor prognosis and a low survival rate. Current therapies for melanoma-metastasis of the lung include surgery…

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New Imaging Method Reveals Lung Microstructure Insights

Microstructural changes in small airways are characteristic for lung disease such as chronic obstructive lung disease (COPD). Spirometry is the common…

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Efficient Handling of 68Ge/Ga Generator Eluates for PET

The positron emitting radionuclide 68Ga (T½ = 68 min) shows great potential for clinical Positron Emission Tomography (PET). The present procedure purifies…

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New Anti-Inflammatory Compound Class Targets Selectins

Selectins (cell adhesion molecules) exhibit functional importance in pathophysiological states of the immune and cardiovascular systems which makes them…

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Two-Colour Fluorescence Marker Boosts Neurodegenerative Research

Worldwide it is estimated that there are 29 million cases of Alzheimer Disease (AD) and about 4 million of Parkinson's Disease (PD). The world market for AD…

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