Technology Offerings

Technology Offerings

Innovative Esterase Monitor for Protein Synthesis In Vitro

Thermostable, fast-folding esterase 2 from Alicyclobacillus acidocaldarius serves as a reporter enzyme to monitor in vivo or in vitro expression of eukaryotic…

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Discover New Trialkylborate Compounds for Advanced Syntheses

A new category of borate compounds enables syntheses, which are difficult to realize, like the synthesis of duroplast precursors, ceramics and metal amides.

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New Somatostatin Substances Target Neuropathic Pain Relief

Neuropathic pain is rather resistant

to conventional analgesics. Therefore,

different approaches must be

taken to treat neuropathic pain. One

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Lipid Implants: Controlled Release for Biotech Drugs

The invention is a lipid based implant, produced by screw extrusion. To achieve good extrudability, very homogeneous drug distribution, excellent mechanical…

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New Depot System Transforms Protein Delivery with VPG Gels

The invention is a lipid based delivery systems based on a vesicular phospholipid gel (VPG) formulation comprising tightly packed liposomes. Protein…

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Early and differential diagnosis test for Alzheimer’s disease

Alzheimer‘s disease (AD), widely regarded

as the most common cause of dementia,

is a progressive neurological disorder. It

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New FRET Method Enhances Hsp90 High-Throughput Screening

The molecular chaperone heat shock protein 90 (Hsp90) couples ATP hydrolysis

to conformational changes driving a reaction cycle that is required

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Arylisoquinolines: New Agents Against Biofilm and Infections

Supply of novel, highly effective and non-toxic agents

– Improved prevention of biofilm-formation

– Treatment of infectious diseasesFurther Information: PDF Bayerische Patentallianz GmbH…

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Innovative Antitumoral Compounds from Tropical Lianas

Plants are an important source of pharmacologically active substances. The tropical

lianas of the families Dioncophyllaceae and Ancistrocladaceae are rich in…

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Boosting Plant Biomass: Carbohydrate Alterations Combat Pathogens

Carbohydrates are generated by photosynthesis in green plant cells. In higher plants

they are transported from green tissues (source tissue) to other parts…

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Unlocking Biotech Potential: Sulfolobus Shuttle Vector Insights

Sulfolobus spp., a thermoacidophilic crenarchaeote, can be easily grown in

the laboratory and is interesting from a biotechnological point of view. Due

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Nucleoside Analogs and Inhibitors Target Epithelial Cancer Stem Cells

Epithelial cancers are among the most

frequent causes of death. Especially

pancreatic carcinomas are characterized

by early metastatic spread and…

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The potent TGF-β antagonist Norrin as a new drug for the treatment of fibrotic diseases and cancer

Human Norrin protein has been originally identified in the art as being a crucial

factor in the development of Norrie disease and is thought to be…

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Mouse Models Reveal Cacna2d2 Gene Insights for Drug Research

Cacna2d2 gene variant leading to voltage-gated calcium channels with modified properties. entla-mice show ataxia, paroxysmal dyskinesia, and epileptic…

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New IL-3 Blockade Strategy Shows Promise for RA Therapy

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory

disorder that attacks the joints producing an inflammatory synovitis. About 1% of the world‘s…

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Discovering Reversible Cathepsin B Inhibitors for Key Health Issues

Cathepsin B is an abundant and ubiquitously expressed cysteine peptidase involved in many pathological processes, such as inflammation, parasite infection and…

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