Thermostable, fast-folding esterase 2 from Alicyclobacillus acidocaldarius serves as a reporter enzyme to monitor in vivo or in vitro expression of eukaryotic…
Solubilization of hydrophobic drugs is a key issue in pharmaceutical industry. Currently, there are few non-toxic formulations available for drugs like…
Cataract is the leading cause of preventable blindness in elderly or diabetic patients worldwide. With a simple surgical technique, the opaque lens can be…
Apoptosis is a highly conserved process regulating the balance between cell death and proliferation for the maintenance of tissue homeostasis. Inhibitor of…
Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and prion diseases share molecular mechanisms including protein aggregation and…
Magnetic nanoparticles provide a multitude of technical applications like magnetic resonance imaging, hyperthermic treatment of cancer, drug delivery,…
Cardiovascular diseases, cancers, immune diseases and mental development of children are related to the fatty acid composition of circulating lipids and…
Pathogenic microbes possess sophisticated molecular tools to suppress the immune response of their mammalian hosts. Recently, a novel mechanism used by…
The following invention is a new, peptide based vaccination against genetical stable tumor stroma-associated antigens. Because of significant upregulation of…
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that attacks the joints producing an inflammatory synovitis. Current treatment options…
Proteins of the Lancefield group A haemolytic streptococci (Streptococcus pyogenes) share amino-acid sequence homologies with various human proteins. As a…
The treatment of IP-10 mediated inflammatory diseases, especially inflammatory bowel diseases, is hampered by lack of treatment effects in some patients and a…
It was surprisingly found that the pyridinylidene hydrazone derivatives inhibit AChE and BuChE as well as Aβ fibril formation significantly. They can destroy…
The invention describes coloured nanoparticles that are dispersed in water. This kind of nano-ink can be used for ink jet cartridges, toners and for industrial…
Organometallic reagents serve as a highly diverse toolkit for synthetic organic chemists. The invention highlights a new MgCl2 mediated addition of organozincs…
This invention comprises light-emitting organometallic compounds (triplet emitters) for the use in OLED devices. A good solubility of this compouds enables an…
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