Due to the fluctuating power production and periods of peak demand, node potentials and line currents in the power grid can reach critical values which may be inacceptable for grid infrastructure. The proposed hierarchical model- based predictive control proposes optimal consumption constraints to consumers at critical times in order to secure reliability and safety of the power grid.
<b>Abstract</b>
Researchers from Goethe University Frankfurt am Main developed a new method to increase proliferation and viability of immune cells, e.g. natural killer (NK) cells, derived from patients or donors. The obtained NK cell preparations are currently tested preclinically for treatment of leukemia.
Currently, pillow-plate heat exchangers (PPHE) enjoy growing attention and become increasingly employed in various branches of industry. The ongoing expansion of the PPHE exploitation area generates a need for new structural requirements for this type of equipment. In this regard, the flow configuration in PPHE is crucial for key aspects like energy efficiency, operating costs and functionality. Whereas in conventional PPHE the flow can be redirected by baffles made of welding lines in the inner pillow-plate channels, there is no method to improve the flow configuration in the outer channels.
For this reason, a new PPHE was developed in the group of Professor Kenig at the University of Paderborn, which enables the flow redirection also in the outer channels. A German patent application is pending, international applications are possible. On behalf of the University of Paderborn, PROvendis offer licenses to interested companies.
The magnetic coupling is capable of transmitting
torque over a hermetically separated distance as a radial magnetic coupling and at smaller dimensions as an axial magnetic coupling. An application might be in a heart catheter pump, where the maximum size is an important and a strong limiting factor.
Sensitive optical components such as semi-conductor laser diodes must be protected from back reflection. A conventional solution to this problem are Faraday optical diodes, which suffer verious problems. We offer a
novel, performant optical diode exploiting spin-orbit coupling of light.
The use of pillow-plate heat exchangers in process industries has been continuously increasing. Usually, the heating or cooling medium flows through the inner channels of the pillow plates, while the process medium flows through the outer channels. The welding spots have an important influence on the three-dimensional structure of the plates and hence on the heat transfer characteristics of the apparatus. However, the welding spots themselves are largely passive with regard to heat transfer.
In the group of Professor Kenig, at the University of Paderborn, the design types used so far were further developed in order to increase the performance. This pillow-plate heat exchanger can be used for all relevant heat transfer applications in the chemical or process industry. This includes processes with phase change (condensation/evaporation). A typical application area is distillation, where pillow-plate heat exchangers can be used as integrated head condenser or reboiler. Further applications are processes with single-phase media on both sides of the apparatus.
A German patent application is pending, international applications are possible. On behalf of the University of Paderborn PROvendis offers licenses to interested companies.
Synthesis and use of two new high performing explosives: bis(3,4,5 trinitropyrazolyl)methane (UMX1 or BTNPM) and bis(3,5 dinitro 4 aminopyrazolyl)methane (UMX2 or BDNAPM)
The present new therapeutic lysosomal lipase A antagonist Lalistat is a convenient and reliable pharmaceutical agent to prevent virus infections such as HCV, Influenza Typ A (H5N1) and other virus infections without any risks of reinfections and development of resistance mutations.
Bei der Innovation handelt es sich um biokompatible Nano-, Meso- und Mikropolymerpartikel zur Bindung pathogener Proteine, die in den Lining Layer der Lunge eindringen.
Die Innovation ermöglicht die Prävention und Behandlung von Lungenerkrankungen, die mit einem Anstieg der Oberflächen-spannung in der Lunge und einer Schädigung des pulmonalen Surfactants einhergehen.
During a joint research project scientists at the University of Stuttgart and the University of Konstanz developed an ECM with functional groups (clickECM) which is covalently and thus firmly bonded to surfaces via bioorthogonal ligation reactions. The fixed bonding obtained through the click reaction also ensures that the clickECM coating, e.g. when used for cell culture vessels, withstands extensive washing. The coating is highly stable and can be produced economically without any costly purification or isolation processes. The clickECM only differs from a natural ECM in terms of the introduced functional group.
Scientists of the University of Duisburg-Essen developed a platform, which facilitates the detection of deletions and insertions as well as point mutations in target genes from a variety of sources against a huge background of wild type alleles, making a clear “Yes” or “No” output possible and thereby simplifying therapeutic decisions.
Neither expensive and complicated equipment nor specialized personnel is needed. The assay is robust and applicable in all laboratories equipped with an RT-PCR machine. It can easily be established for point of care (PoC) purposes.
This sensitive technology now enables clinicians to be independent of the scarce resource “tissue biopsy”. By using blood (ctDNA, cfDNA or CTC) it opens new non-invasive possibilities for monitoring the mutation status of patients before and during treatment as well as to detect disease relapse early. A European and a US patent have already been granted, other applications are pending.
Invention is used for additive manufactur-ing of parts out of amorphous or partly crystalline metals with low melting point. This is done with an extrusion method. The used material, metal granulate, is heated up to the glass transition temperature and partly up to the melting temperature. By doing so, the material is moved into a thermoplastic state. After heating, the material can then be extruded by pressure and is selectively placed onto a building platform. The system described in this invention is able to manufacture hollow constructions along with complex parts, all with good mechanical properties. Due to the generating of the part onto the building platform it is not necessary to clean or post process the part as it would be with other methods.
Advances in neurosciences are linked to neuron stimulation. Our technology presents the use of Schottky miniaturized photovoltaic cells for this goal, showing remarkable advantages respect stablished techniques, as Patch clamp or Optogenetics.
When producing rear contact solar cells, both negatively and positively doped areas need to be produced on the rear of the solar cell. Moreover, the front side of the solar cell has to be sufficiently passivated in order to minimize surface recombination. This means three differently doped areas are required.
Scientists of the University of Konstanz have now developed a new method for producing these three areas in a single diffusion step. This approach is based on the application of a borosilicate glass layer and partial silicon nitride masking on the rear of the solar cell.
Scientists at the University of Stuttgart have developed an absorption chiller that is extremely compact, lightweight and stable in terms of operation, even at low evaporator temperatures and high heat rejection temperatures. Because of its compactness the absorption chiller has lower production costs and requires less refrigerant than conventional absorption chillers.
The invention discloses two chemical compound families derived from tetrahydrotriazine or coumarin selectively targeting the autophagic pathway.
Feedback
