Young stars ejecting plasma could give us clues into the Sun’s past Kyoto, Japan — Down here on Earth we don’t usually notice, but the Sun is frequently ejecting huge masses of plasma into space. These are called coronal mass ejections (CMEs). They often occur together with sudden brightenings called flares, and sometimes extend far enough to disturb Earth’s magnetosphere, generating space weather phenomena including auroras or geomagnetic storms, and even damaging power grids on occasion. Scientists believe that when…
Alzheimer's Disease (AD) is the main neurodegenerative disease worldwide affecting more than 15 Mill. people. An easy AD blood diagnostic method does not…
Scientists at the University of Göttingen identified a new use of Mediators and developed a binder-free production procedure of wood composites and timber…
Scientists at the University of Göttingen developed new very light wood composites, boards and panels on renewable sources, replacing wood in a high percentage…
Scientists at the Georg-August-University Göttingen produced different monoclonal antibodies directed against phosphorylation sites of CCR5. These antibodies…
Scientists at the Georg-August-University produced a monoclonal antibody which recognises murine CD197, a 43kD member of the G coupled receptor family, which…
Scientists at the Georg-August-University Göttingen produced different monoclonal antibodies directed against phosphorylation sites of CCR5. These antibodies have been demonstrated to exclusively recognise CD195 phosphorylated at Ser 337 or Ser 349. Human CD195 is a member of the G protein coupled superfamily of receptors, which acts as a receptor for a member of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells. It plays a key role in regulating the activation and migration of leukocytes. CD195 is expressed by a subset of T-lymphocytes and by monocytes. Using these antibodies e.g. in combination with our indicator cell line ligand induced phosphorylation or dephosphorylation of CCR5 can be directly measured without using more indirect indicators like Ca++ concentrations.
This principle can be extended to measure activation states of G protein coupled receptors or activity of GPCR kinases generally, e.g. when screening for new agonists, antagonists or GRK inhibitors.
Scientists of the University of Göttingen developed new highly potent drugs (with an IC50 in the pico-Molar range) as well as a selective tumor therapy through…
The invention relates to functionalised diols of diamondoids in which one of the two hydroxy groups is masked by a protective group, and to methods for…
The novel design is a first attempt to systematically scale up from traps that hold a few ions in a few locations to large trap arrays that can process many…
NASA's Fermi Gamma-Ray Space Telescope maps gamma rays, radiation that typically packs 100 billion times the energy of radio waves. Nevertheless, and to the…
The microcosm, the realm of quantum physics, is ruled by probability and chance. The behaviour of quantum particles cannot be predicted with certainty but only…
A new physical quantity of electrons—orbital angular momentum—has been generated by Masaya Uchida and Akira Tonomura at the RIKEN Advanced Science Institute in…
It’s a measure of the astonishing progress in nanotechnology that questions that once would have interested only physicists or chemists are now being asked by…
At a German University a manufacturing technique suitably for membrane electrodes was developed. The main advantage is the usage of less platinum (up to 30%),…
The invention at hand provides, for the first time, thermally stable trisaryl compounds of the rare earth metals which are storable for a long time. These…
“Microsoft and Apple aren't going to open up all their stuff. But they all create programs that put pixels on the screen. And if we can modify those pixels,…
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