Yellow mosaic virus disease leads to substantial losses – up to 50 % of the yield – in susceptible barley varieties (Hordeum vulgare). The disease is caused by different strains of Barley yellow mosaic virus (BaYMV) and Barley mild mosaic virus (BaMMV). It cannot be cured by chemical treatment. The present invention provides a new recessive resistance gene. Variants of the gene lead to resistance against all agents known to cause yellow mosaic virus disease in Europe.

Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. The problem is solved by providing Direct Injectable Polymer Solutions (DIPOs) which act as a depot after administration. Their polarity and degradation rate is adjustable. They are much less acidic compared to PLA/PLGA polymers.

Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. Direct Injectable OleoGels (DIOGs) and In Situ Forming OleoGels (ISFOGs) were developed as new, biodegradable and lipid based formulations for parenteral controlled release applications. Both formulations have many advantages in terms of manufacturability, rheological properties and release control compared to the currently used drug delivery systems.

DNA assembly methods such as such as Gibson and Golden Gate cloning are basic tools for synthetic biology. Both methods allow assembly of constructs from multiple DNA fragments in a one-pot one-step assembly reaction. Standardization of parts is another essential element of modern synthetic biology. A novel method has been developed to assemble constructs from several individual DNA parts – each kept on a solid carrier – directly in a one-pot one-step reaction.

Dendrimers are spherical, highly branched polymers used in the fields of drug delivery and drug targeting, DNA/RNA delivery, imaging, protein labelling, protein crosslinking and protein separation, coagulation inhibition, and surface, cell and tissue recognition. They are also used as macroamphiphiles and catalyst supports. All previously existing dendrimers require special, branched and partially protected or polyreactive building blocks for their synthesis. A disadvantage is the limited range of dendrimers with varying structures that can be produced, and the concentration to few dendron forming functional groups.
The new technology offers the possibility of synthesising dendrimers with almost any combination of branch lengths, degree of branching, internal and terminal groups. This is achieved by means of multiple iterative multicomponent reactions, e.g. with acidic, alkaline, hydrophilic, lipophilic, sugar and other functional groups.

Electromagnetic pulses lasting one millionth of a millionth of a second may hold the key to advances in medical imaging, communications and drug development….

The study, published in Nature Communications, helps to confirm novel theoretical work that attempts to explain how electrons behave in these strange…

Astronomers at Lomonosov Moscow State University in cooperation with their French colleagues and with the help of citizen scientists have released «The…

Why do the majority of astronomers believe in dark matter: matter whose composition is unknown but which seems to make up 80% of the mass of the galaxies?

The Technology provides a new and outstanding method for the enhancement of the
quality of dim images. Inspired by the spatial integration of visual information in
nocturnal insects, the algorithm successfully enhances the contrast and brightness of
dim images and removes noise while preserving fine details and object contours. The
patented system is applicable to field programmable gate arrays (FPGA) or image
processors, which offer parallel computing capabilities. A wide variety of capabilities
and markets from automotive sector to the enhancement of diagnostic images can be
addressed.

A giant black hole ripped apart a nearby star and then continued to feed off its remains for close to a decade, according to research led by the University of…

The CO2 level in Mars' primitive atmosphere 3.5 billion years ago was too low for sediments, such as those found by NASA's Curiosity exploration vehicle in…

Unavoidably, each digital information we send around the globe is prone to be lost. Travelling long ways in wires, the initial signal decays and scatters by…

Researchers from the University of Oldenburg, Germany, developed a laser cantilever anemometer (LCA) which utilizes the laser pointer principle of a scanning-force microscope to capture the velocity and the angle of fluid flows.

As yet there has been no satisfactory and easy method to determine the concentrations of substances dissolved in liquid product flows. Previous methods using sensors were not sufficiently reliable and not designed for flow-through systems. Or they required that the analyte whose concentration was to be determined was already known. The device according to invention makes it easy to determine the analyte in a liquid phase both qualitatively and quantitatively.
The Carl von Ossietzky University in Oldenburg, Germany, developed a method which serves the purpose of identifying and quantifying substances (proteins, amino acids, drug constituents) in solution.

The Carl von Ossietzky University in Oldenburg, Germany, developed a method which markedly improved the quantitative determination of hydrogen. A so-called TPR is conducted by coupling a flame ionization detector (FID) to a methanizer. Adding a certain amount of carbon monoxide (CO) and an excess amount of hydrogen immediately upstream of the FID, CO will react with hydrogen to yield methane. Methane produces a FID signal which is proportional to the amount of hydrogen in the sample.