Ten construction workers will often get a job done faster than one. But in digging a deep well, for instance, ten workers are a waste of human resources: the diggers can’t work simultaneously, as the second worker isn’t able to start digging until the first one has finished, and so on.
A similar challenge is encountered by scientists who study the structure and dynamics of molecules using nuclear magnetic resonance (NMR) spectroscopy. This technique serves as an essential tool in understanding numerous molecules – including proteins, nucleic acids and active pharmaceuticals – in their natural surroundings. It does this by exposing them to electromagnetic radiation and studying the dispersion patterns of the electromagnetic waves that hit the molecules. However, to obtain a full NMR picture of such complex molecules one needs to perform numerous measurements that are based on the same “serial” principle as well digging: hundreds or thousands of one-dimensional scans need to be performed one after the other; these scans need then to be combined to create a unified multidimensional picture of the molecule. While a single scan may take a fraction of a second, multidimensional procedures may last several hours or even days.
A team led by Prof. Lucio Frydman of the Weizmann Institute’s Chemical Physics Department has now found a way to perform multidimensional NMR with a single scan. The new method, described in the December 2002 issue of the Proceedings of the National Academy of Sciences USA (PNAS), is expected to significantly speed up molecular studies routinely performed in diverse fields.
Alex Smith | EurekAlert!
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Microelectronics as a key technology enables numerous innovations in the field of intelligent medical technology. The Fraunhofer Institute for Biomedical Engineering IBMT coordinates the BMBF cooperative project "I-call" realizing the first electronic system for ultrasound-based, safe and interference-resistant data transmission between implants in the human body.
When microelectronic systems are used for medical applications, they have to meet high requirements in terms of biocompatibility, reliability, energy...
Thomas Heine, Professor of Theoretical Chemistry at TU Dresden, together with his team, first predicted a topological 2D polymer in 2019. Only one year later, an international team led by Italian researchers was able to synthesize these materials and experimentally prove their topological properties. For the renowned journal Nature Materials, this was the occasion to invite Thomas Heine to a News and Views article, which was published this week. Under the title "Making 2D Topological Polymers a reality" Prof. Heine describes how his theory became a reality.
Ultrathin materials are extremely interesting as building blocks for next generation nano electronic devices, as it is much easier to make circuits and other...
Scientists took a leukocyte as the blueprint and developed a microrobot that has the size, shape and moving capabilities of a white blood cell. Simulating a blood vessel in a laboratory setting, they succeeded in magnetically navigating the ball-shaped microroller through this dynamic and dense environment. The drug-delivery vehicle withstood the simulated blood flow, pushing the developments in targeted drug delivery a step further: inside the body, there is no better access route to all tissues and organs than the circulatory system. A robot that could actually travel through this finely woven web would revolutionize the minimally-invasive treatment of illnesses.
A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell...
By studying the chemical elements on Mars today -- including carbon and oxygen -- scientists can work backwards to piece together the history of a planet that once had the conditions necessary to support life.
Weaving this story, element by element, from roughly 140 million miles (225 million kilometers) away is a painstaking process. But scientists aren't the type...
Study co-led by Berkeley Lab reveals how wavelike plasmons could power up a new class of sensing and photochemical technologies at the nanoscale
Wavelike, collective oscillations of electrons known as "plasmons" are very important for determining the optical and electronic properties of metals.
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