Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists in Japan Design First Optical Pacemaker for Laboratory Research

03.06.2008
The world's first optical pacemaker is described in an article published today in Optics Express, the Optical Society’s open-access journal. A team of scientists at Osaka University in Japan show that powerful, but very short, laser pulses can help control the beating of heart muscle cells.

"If you put a large amount of laser power through these cells over a very short time period, you get a huge response," says Nicholas Smith, who led the research. The laser pulses cause the release of calcium ions within the cells, Smith explains, and this action forces the cells to contract.

This technique provides a tool for controlling heart muscle cells in the laboratory, a breakthrough that may help scientists better understand the mechanism of heart muscle contraction.

One potential application of this technology is in studying uncoordinated contractions in heart muscle. Normally, heart muscle contracts in a highly coordinated fashion, and this is what allows the heart to pump blood through the vasculature. But in some people, this coordinated beating breaks down, and the heart twitches irregularly—a condition known as fibrillation.

The new laser technique may allow scientists to create a form of fibrillation in the test tube. The lasers can destabilize the beating of the cells in laboratory experiments by introducing a beat frequency in one target cell distinct from the surrounding cells. This would allow scientists to study irregular heart beats on a cellular level and screen anti-fibrillation drugs.

Outside the laboratory, exposing heart muscle cells to powerful laser pulses can have its drawbacks. Although the laser pulses last for less than a trillionth of a second, damaging effects can build up over time and this currently limits the possibility of clinical applications.

This work was supported by the Japan Science and Technology organization.

Paper: "A Femtosecond Laser Pacemaker for Heart Muscle Cells," N.I. Smith et al, Optics Express. Complete paper available on request.

About OSA

Uniting more than 70,000 professionals from 134 countries, the Optical Society (OSA) brings together the global optics community through its programs and initiatives. Since 1916 OSA has worked to advance the common interests of the field, providing educational resources to the scientists, engineers and business leaders who work in the field by promoting the science of light and the advanced technologies made possible by optics and photonics. OSA publications, events, technical groups and programs foster optics knowledge and scientific collaboration among all those with an interest in optics and photonics.

Colleen Morrison | newswise
Further information:
http://www.osa.org
http://www.aip.org

More articles from Physics and Astronomy:

nachricht Spintronics: Researchers show how to make non-magnetic materials magnetic
06.08.2020 | Martin-Luther-Universität Halle-Wittenberg

nachricht Manifestation of quantum distance in flat band materials
05.08.2020 | Institute for Basic Science

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: ScanCut project completed: laser cutting enables more intricate plug connector designs

Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.

Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...

Im Focus: New Strategy Against Osteoporosis

An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.

Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...

Im Focus: AI & single-cell genomics

New software predicts cell fate

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...

Im Focus: TU Graz Researchers synthesize nanoparticles tailored for special applications

“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.

Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...

Im Focus: Tailored light inspired by nature

An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.

Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“Conference on Laser Polishing – LaP 2020”: The final touches for surfaces

23.07.2020 | Event News

Conference radar for cybersecurity

21.07.2020 | Event News

Contact Tracing Apps against COVID-19: German National Academy Leopoldina hosts international virtual panel discussion

07.07.2020 | Event News

 
Latest News

Rare Earth Elements in Norwegian Fjords?

06.08.2020 | Earth Sciences

Anode material for safe batteries with a long cycle life

06.08.2020 | Power and Electrical Engineering

Turning carbon dioxide into liquid fuel

06.08.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>