The branched capillary structure, feeding adipose tissue in a living mouse, is revealed with multiphoton fluorescence microscopy as nanocrystal quantum dots circulate through the bloodstream. Credit: Bioimaging Resource/Cornell University
Copyright © Cornell University
Multiphoton fluorescence microscopy with quantum dots illuminates a capillary beneath the skin of a living mouse. In this image, collagen is imaged in blue by second harmonic generation while quantum dots inside the capillary are imaged in yellow by two-photon fluorescence excitation. Because red blood cells exlude the quantum dots, they appear as shadows within the capillaries, which can be monitored over time (yellow trace at bottom of image). Credit: Bioimaging Resource/Cornell University. Copyright © Cornell University
Tiny blood vessels, viewed beneath a mouse’s skin with a newly developed application of multiphoton microscopy, appear so bright and vivid in high-resolution images that researchers can see the vessel walls ripple with each heartbeat -- 640 times a minute.
The capillaries are illuminated in unprecedented detail using fluorescence imaging labels, which are molecule-size nanocrystals called quantum dots circulating through the bloodstream. Quantum dots are microscopic metal or semiconductor boxes (in this case cadmium selenide-zinc sulfide) that hold a certain number of electrons and, thus, have a wide number of potential applications in electronics and photonics.
Writing in the latest issue of the journal Science (May 30, 2003), researchers at Cornell University and a nanocrystal manufacturer, Quantum Dot Corp., report that the nanocrystals are particularly useful for producing high-resolution, three-dimensional images inside living.
Roger Segelken | Cornell News
How do muscle and tendon connections last a lifetime? Study in the fruit fly Drosophila
04.04.2019 | Westfälische Wilhelms-Universität Münster
The Internet of Things: TU Graz researchers increase the dependability of smart systems
18.02.2019 | Technische Universität Graz
A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter
A localization phenomenon boosts the accuracy of solving quantum many-body problems with quantum computers which are otherwise challenging for conventional computers. This brings such digital quantum simulation within reach on quantum devices available today.
Quantum computers promise to solve certain computational problems exponentially faster than any classical machine. “A particularly promising application is the...
The technology could revolutionize how information travels through data centers and artificial intelligence networks
Engineers at the University of California, Berkeley have built a new photonic switch that can control the direction of light passing through optical fibers...
Physicists observe how electron-hole pairs drift apart at ultrafast speed, but still remain strongly bound.
Modern electronics relies on ultrafast charge motion on ever shorter length scales. Physicists from Regensburg and Gothenburg have now succeeded in resolving a...
Engineers create novel optical devices, including a moth eye-inspired omnidirectional microwave antenna
A team of engineers at Tufts University has developed a series of 3D printed metamaterials with unique microwave or optical properties that go beyond what is...
17.04.2019 | Event News
15.04.2019 | Event News
09.04.2019 | Event News
18.04.2019 | Life Sciences
18.04.2019 | Physics and Astronomy
18.04.2019 | Life Sciences