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Health & Medicine
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New Insights Into Targeting Stomach Bug Virus Treatment

New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…

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Health & Medicine

Natural Oils Tested on In Vitro Skin Models for Skincare

For some years now, the trend in the cosmetics and skincare sector has been toward transparency and natural, sustainable ingredients. A growing number of consumers are rejecting cosmetics that contain petroleum-derived mineral oils and silicone oils. As a result, manufacturers are increasingly turning toward plant-based oils, fats, and waxes as substitutes. Working in tandem with Kneipp GmbH, a producer of cosmetic products and other items, the Fraunhofer Institute for Silicate Research ISC is conducting the first-ever systematic tests of the…

Life & Chemistry

How Plants Conquered Earth: Insights from Molecular Research

An international research team is examining the molecular mechanisms that enabled plants to colonize the surface of the Earth. Around 550 million years ago, the Earth’s surface was a barren land mass surrounded by oceans. Almost all lifeforms that had evolved up to that point existed exclusively in the oceans. Then, however, the first plants made their way onto land—not only making the Earth greener but also fundamentally transforming the atmosphere, the climate and overall conditions of life on our…

Medical Engineering

Sea Slugs Inspire Stretchable Biomedical Sensors for Health

USC Viterbi School of Engineering researcher Hangbo Zhao presents findings on highly stretchable and customizable microneedles for application in fields including neuroscience, tissue engineering, and wearable bioelectronics. The revolution in personalized medicine is well underway – with wearable devices and DIY home testing, it’s easier than ever to track everything from heart rate, to glucose levels, to microbiome diversity. However, there’s still an innovation gap before we achieve a seamless interface between the human body and invasive monitoring devices. That’s…

Life & Chemistry

Nanotubes and Antibodies Boost Fentanyl Detection Sensitivity

New sensor is six orders of magnitude more sensitive than the next best thing. A research team at Pitt led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich School of Arts and Sciences, has developed a fentanyl sensor that is six orders of magnitude more sensitive than any electrochemical sensor for the drug reported in the past five years. The portable sensor can also tell the difference between fentanyl and other opioids. Their work was published in the…

Life & Chemistry

Ocean Currents: Microscopic Organisms’ Expressway to Depths

New research shows how tiny plant-like organisms hitch a ride on ocean currents to reach darker and deeper depths, where they impact carbon cycling and microbial dynamics in the subtropical oceans. Some of the ocean’s tiniest organisms get swept into underwater currents that act as a conduit that shuttles them from the sunny surface to deeper, darker depths where they play a huge role in affecting the ocean’s chemistry and ecosystem, according to new research. Published in the Proceedings of…

Medical Engineering

FDmiX: Streamlining Nanoparticle Production for mRNA Vaccines

Nucleic acid-based medications such as mRNA vaccines are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are needed inside the body’s cells. The Fraunhofer Institute for Production Systems and Design Technology IPK and FDX Fluid Dynamix GmbH have worked together to develop a technology platform for the production of nanoparticles that can achieve particle quality and stability at levels previously out of reach: FDmiX (Fraunhofer Dynamic Mixing…

Medical Engineering

New Breath Sensor Offers Real-Time Oxygen Monitoring

Oxygen saturation in the blood that is either too low or too high can cause physical harm or even death. This is why patients’ oxygen concentraions are monitored continuously in both intensive care and trauma units. However, the pulse oximeters clipped onto a patient’s fingertip for this purpose can be unreliable. Researchers at the Fraunhofer-Gesellschaft have developed a fluorescence-based sensor that measures the oxygen content of people’s breath directly and in real time. The sensor determines the oxygen concentration in…

Life & Chemistry

New Plant Regeneration Method Bypasses Phytohormones

…without the application of phytohormones. Researchers develop a novel plant regeneration approach by modulating the expression of genes that control plant cell differentiation.  For ages now, plants have been the primary source of nutrition for animals and mankind. Additionally, plants are used for the extraction of various medicinal and therapeutic compounds. However, their indiscriminate use, along with the rising demand for food, underscores the need for novel plant breeding practices. Advances in plant biotechnology can address the problems associated with…

Life & Chemistry

Closing the Carbon Cycle: A Path to Net-Zero Emissions

A holistic approach to reach net-zero carbon emissions across the economy. A major approach to achieving net-zero carbon emissions relies on converting various parts of the economy, such as personal vehicles and heating, to run via electricity generated from renewable sources. But carbon cannot be removed from all parts of society. Plastics, ubiquitous in the modern world, cannot be decarbonized because they are made of carbon-based molecules. Led by chemist Wendy Shaw of Pacific Northwest National Laboratory (PNNL), a multi-institutional…

Health & Medicine

New Regulator of Eating Behavior Discovered in Obesity Research

The rapidly escalating prevalence of overweight and obesity poses a significant medical challenge worldwide. In addition to people’s changing lifestyles, genetic factors also play a key role in the development of obesity. Scientists at Leipzig University and Heinrich Heine University Düsseldorf have now identified a new regulator of eating behaviour. The findings have been published in the internationally renowned Nature journal Signal Transduction and Targeted Therapy. “Our research underscores our incomplete understanding of the factors governing food intake. It also…

Health & Medicine

New Antibacterial Substance from Bacteria Offers Hope Against Resistance

Antibacterial substance from staphylococci discovered with new mechanism of action against natural competitors. Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment. Researchers at the University Hospital Bonn (UKB), the University of Bonn and the German Center for Infection Research (DZIF) have discovered a new so-called lantibiotic, namely epilancin A37. It is produced by staphylococci that colonize the skin and acts specifically against their main competitors there, the corynebacteria. This specificity is presumably…

Health & Medicine

Researchers have found brown fat’s “off-switch

Researchers from the University of Southern Denmark, the Novo Nordisk Center for Adipocyte Signaling (SDU), the University of Bonn and the University Hospital Bonn (UKB) have found a protein that is responsible for turning off brown fat activity. This new discovery could lead to a promising strategy for safely activating brown fat and tackling obesity and related health problems. The results of the study have now been published in the journal „Nature Metabolism“. Brown fat, also known as brown adipose…

Life & Chemistry

Immune System Insights: Learning from Harmless Particles

Our lungs are bombarded by all manner of different particles every single day. Whilst some are perfectly safe for us, others—known as pathogens—have the potential to make us ill. The immune system trains its response whenever it encounters such a pathogen. Yet researchers at the University of Bonn have now shown that even harmless particles help to improve the immune response and have published their results in the journal “Nature Immunology.” An adult takes around 12 breaths a minute, filling…

Health & Medicine

New Biomarkers Enhance CAR T Cell Therapy for Bone Marrow Tumours

CAR T cell therapy has proven effective in treating various haematological cancers. However, not all patients respond equally well to treatment. In a recent clinical study, researchers from the University of Leipzig Medical Center and the Fraunhofer Institute for Cell Therapy and Immunology identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow. The findings have been published in the prestigious journal Nature Cancer. CAR…

Life & Chemistry

Understanding Tomato Root Communication: Ora Hazak’s Insights

Ora Hazak has always been fascinated by plants and is studying the signals that roots send to the rest of the organism. She aims to understand this communication in order to develop climate change-resistant crops. Ora was just three when her mother first asked her to water the plants. It was a request that kindled a passion that has not ebbed since. She was 15 when she first attempted to cross red and white garden balsam, obtaining a mixture of…

Life & Chemistry

Recovering Phosphorus From Sewage Sludge Ash: A Sustainable Solution

Chemical and heat treatment of sewage sludge can recover phosphorus in a process that could help address the problem of diminishing supplies of phosphorus ores. Valuable supplies of phosphorus could be recovered from sewage sludge ash, which remains after the sludge has been burned for electric power generation. The method has been developed by chemical engineers Yuuki Mochizuki and Naoto Tsubouchi at Hokkaido University’s Center for Advanced Research of Energy and Materials. Their work is published in the journal Resources,…

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