New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
New data from a 1998 study to assess the potential risks of chromosomal abnormalities of residents living near landfill sites is detailed in a research letter in this week’s issue of THE LANCET. The findings suggest that the increased risk of chromosomal abnormalities is of a similar magnitude to the increased risk of non-chromosomal abnormalities previously reported.
Previous findings of the EUROHAZCON study (Lancet 1998; 352: 423–27) showed a 33% increase in the risk of non-chromosomal ano
Chemists at Utrecht University have developed a catalyst for fine chemistry. Tiny tubes of graphite are the carrier for this catalyst. PhD student Tijmen Ros successfully tested the catalyst with a standard reaction. Fellow researchers are now making the catalyst suitable for the production of cinnamon alcohol, an aromatic substance and flavouring.
According to the researchers from Utrecht, carbon nanofibres will replace active carbon as a carrier for catalysts. Carbon nanofibres are small t
Researchers from the Erasmus University in Rotterdam have demonstrated that a gene helps in the neat repair of DNA. Without this gene the body would repair damaged DNA in a careless manner more often. This causes new damage, which can lead to cancer.
The careless repair of damaged DNA can cause mutations and can result in cancer. Cell biologists from the Erasmus University in Rotterdam studied the repair of double strand breaks. Such breaks can for example arise following radiotherapy.
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An effective, affordable, and accessible HIV vaccine is 7-10 years away, according to scientists at the Medical Research Council of South Africa, in this week’s BMJ. However, its success depends on a complex interplay of politics, science, and public-private partnerships.
Equitable public-private partnerships between researchers, manufacturers, and distributors and partnerships between rich and poor countries are the best strategy for the development of the vaccine, say the authors. Successf
Life on the moons of Jupiter, and a source of healthy polyunsaturated fatty acids and low temperature enzymes that could even make washing powders work at low temperatures: The microbes that live in Antarctic sea ice may hold the answers to a host of everyday applications as well as revealing how life forms might be able to exist on frozen planets. One of those interested in sea ice and the life forms it supports is Dr David Thomas of the University`s School of Ocean Sciences. He is presently the on
A team of Italian researchers has demonstrated in the laboratory for the first time that combining two of the newest anti-cancer targeted agents may produce a powerful new combination against breast cancer – and possibly many other cancers as well. Their findings are reported (Thursday 24 January) in the journal Annals of Oncology.*
They found that trastuzumab (Herceptin) and the as yet unlicensed drug ZD1839 (Iressa), act synergistically against two rogue genes commonly involved in breast c
Combining two separate observations of cells in brain tumours could enable doctors to improve the success rate of radiotherapy. Speaking today (23 January) at the Institute of Physics Simulation and Modelling Applied to Medicine conference in London, chemical engineer Dr Norman Kirkby from the University of Surrey will explain how using the correct time intervals between a sequence of low dose radiotherapy sessions could increase the chance of curing brain cancers that tend to resist treatment.
Combining two separate observations of cells in brain tumours could enable doctors to improve the success rate of radiotherapy. Speaking today (23 January) at the Institute of Physics Simulation and Modelling Applied to Medicine conference in London, chemical engineer Dr Norman Kirkby from the University of Surrey will explain how using the correct time intervals between a sequence of low dose radiotherapy sessions could increase the chance of curing brain cancers that tend to resist treatment.
Researchers at the University of Bristol have discovered that not all babies who wheeze will develop asthma in later life.
Dr Andrea Sherriff and asthma experts from the Institute of Child Health in Bristol and St George`s Hospital Medical School in London studied around 10,000 children taking part in the Children of the 90s project in Bristol.
The researchers discovered that over 60% of babies who wheezed in the first six months had stopped by 3½ years of age. When they we
Genes mean ladies like friends and partners that smell like their father.
Bachelors – ditch the Old Spice and don your prospective father-in-laws clothes. Women prefer the scent of their dad, a study shows, and may choose their friends and partners accordingly.
Nervous new boyfriends can live or die by the nod of a dates daunting dad. But Carole Ober and her team at the University of Chicago in Illinois have found a more fundamental fatherly influence: women prefe
Chimpanzee waste could shed light on the origins and spread of HIV.
Delving into droppings has given AIDS researchers a surprise. Far fewer chimpanzees than they had suspected have SIVcpz, the animal virus most like HIV.
The technique could shed much-needed light on the origins and evolution of the viruses that cause AIDS. “It’s a non-invasive means to study the wild relative of HIV in its natural environment,” says Beatrice Hahn, of the University of Alabama in Birmingham,
The herbal extract, butterbur, is as effective as antihistamines for treating hay fever, and does not have the sedative effects often associated with these drugs, finds a study in this week’s BMJ.
Researchers in Switzerland identified 125 patients with a history of hay fever. Patients received either butterbur extract tablets or a commonly used non-sedating antihistamine (cetirizine) as recommended by the manufacturers.
After two weeks, the effects of butterbur and cetirizine were s
Scientists believe that they have found a chemical responsible for increasing cardiovascular risk, it was revealed. And crucially they have identified how it is made and destroyed in the body raising the possibilty that new drugs to reduce the risk of heart disease are around the corner. A team of scientists based at the new British Heart Foundation (BHF) Laboratories at UCL first identified ADMA as a naturally occurring substance that blocks the production of a gas made by the body – Nitric Oxide. N
A new type of Earth ecosystem could be found on other planets.
Scientists have found a community of microbes unlike anything else on Earth. Conditions in this ecosystem could mimic those on Earth when life began, and might exist elsewhere in today’s Solar System.
Home to the microbes is a hot spring 200 metres beneath the US state of Idaho. Their lives owe nothing to the Sun. They generate energy by combining hydrogen from rocks with carbon dioxide, releasing methane as a by
Adolescents from families where mealtimes and other activities are shared seem to have fewer mental health problems, reports a study in the Journal of Epidemiology and Community Health.
Researchers assessed the family habits and rituals of 82 first time users, aged between 14 and 23, of mental health services in one metropolitan area. Anxiety and depression were the main problems for which treatment was sought. Family practices in 177 young people within the same age band from various educa
Middle aged men should be heartened to know that frequent sex is not likely to increase their risk of stroke. It may actually reduce the risk of sudden death, suggests research in the Journal of Epidemiology and Community Health.
The Caerphilly study, which takes its name from a former mining town in South Wales, involves tracking the development of heart disease in almost 3000 men. All were aged between 45 and 59 when recruited to the study between 1979 and 1983.
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