New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
A cell type with the potential for making the four major types of human tissue has been found in the stomach and small intestine by a Medical College of Georgia researcher.
These VENT cells have been found in addition to the three sources of cells typically associated with gastrointestinal development, says Dr. Paul Sohal, MCG developmental biologist, who first identified these cells nearly a decade ago.
Identification of VENT – ventrally emigrating neural tube – cells within the
While the vision-impaired Hubble Space Telescope needed optical doctoring from shuttle astronauts, vision researchers back on Earth were wondering if the human eye was clever enough to fix itself.
Now a neurobiology study at Cornell University suggests that internal parts of the eye indeed can compensate for less-than-perfect conditions in other parts — either developmentally (during the lifetime of one individual) or genetically (over many generations).
Results of the study, “I
Broad implications seen for treating Alzheimer’s and other human diseases
By teaching fruit flies to avoid an odor and isolating mutant flies that can’t remember their lessons, researchers at Cold Spring Harbor Laboratory in New York have identified dozens of genes required for long-term memory.
In the same study, using DNA chip technology, the scientists identified another large group of candidate memory genes that are either switched on or off in the fly brain during memo
Classifying corals in terms of species is a risky business. Biologist Onno Diekmann from the University of Groningen has discovered that four species of stone corals differ so little in terms of their genetic material that they can scarcely be termed separate species.
Corals are formed by a collection of identical coral polyps which together form a coral colony. Onno Diekmann compared the genetic material from six different species of coral from the Madracis genus, which are found in the co
Researchers at the University of Pittsburgh Cancer Institute (UPCI), in collaboration with Johns Hopkins University School of Medicine have found that a recently discovered gene plays an essential role in mediating apoptosis, or cell death, in colorectal cancer cells. The results are published in the Feb. 18 issue of Proceedings of the National Academy of Sciences.
The gene, PUMA, or p53 up-regulated modulator of apoptosis, is controlled by p53 – a tumor-suppressing gene that prevents norma
The link between climate and cholera, a serious health problem in many parts of the world, has become stronger in recent decades, according to a University of Michigan scientist who takes an ecological approach to understanding disease patterns. Mercedes Pascual, an assistant professor of ecology and evolutionary biology, discussed her work during a symposium Feb. 17 on the ecology of infectious diseases at the annual meeting of the American Association for the Advancement of Science.
In wo
Protein used during cell development important in cloning technique
Researchers at the University of Minnesota have identified the protein responsible for disassembly of donor nucleoli in the context of nuclear cloning. Although it was already known that nucleoli, essential structures for protein synthesis, normally disassemble or disappear for a period of time in the early animal development and also during nuclear cloning, it was not known until this study what causes this phenomeno
Human intelligence is like a mental juggling act in which the smartest performers use specific brain regions to resist distraction and keep attention focused on critical pieces of information, according to a new brain imaging study from Washington University in St. Louis.
“Some people seem to perform better than others in novel, mentally-demanding situations, but why?” asks Jeremy R. Gray, Ph.D., co-author of the study to be posted Feb. 18 in an advance online issue of the journal Nature N
UI researchers discover new mechanism controlling movement of cell structures
Organelles are compartments and structures inside cells that perform varied and vital functions, including energy production, storage and transportation of important substances and removal of waste products. Normal cellular function requires that organelles be positioned in specific locations in a cell. Thus, movement of the organelles to their appropriate destinations is critical.
A team of Univer
Sex and gender scientists explore a revolution in evolution
Darwin may have been wrong about sex. Or at least too narrow minded
At the annual meeting of the American Association for the Advancement of Science, leading researchers and theorists in the evolution of sexual behavior will gather to present the growing evidence that Darwins idea of sexual selection requires sweeping revisions.
I dont have a theory to address it all by any means,
NIAB has patent protection pending for a number of schemes for encoding non-genetic information into DNA. The patent describes four methods by which DNA can be made to hold information in a binary or other number base format as a DNA barcode.
Jonathan White, Head of NIABs Molecular and Genotyping Group said, “The encoding of non-genetic information has the overall major benefit of providing a means of ready identification and authentication of goods and organisms and is particul
Educators and scientists should discard the idea that a cells nucleus is just a bag of chromosomes, according to Johns Hopkins cell biologist Kathy Wilson, Ph.D. In a Feb. 17 session at the annual meeting of the American Association for the Advancement of Science (AAAS) in Denver, Wilson and five others will introduce visual evidence of the nucleuss newly recognized importance.
“The old view is that the nucleus is simply a warehouse for chromosomes,” says Wilson, associate
New molecular technologies, some driven by the work of a researcher at the University of Illinois at Urbana-Champaign, are exposing unexpectedly high levels of DNA folding and complex protein-rich assemblages within the nucleus of cells that he says “seriously challenge the textbook models.”
“What we are seeing suggests that there may be machinery, not yet identified, that controls the folding and the movements of enzymes that turn genes on and off,” said Andrew Belmont, a professor of cell
Scientists work toward unraveling gene expression in the brain
Using Web-based tools they developed to sift through reams of data, scientists from the Kennedy Krieger Institute and Johns Hopkins hope to unravel the genetics of neurological problems associated with Down syndrome, autism and lead poisoning.
Their search starts with microarrays, or so-called “gene chips,” which measure the activity of tens of thousands of genes all at once. By analyzing the pattern of gene acti
UH Researchers Focus On Diagnosing Eye Disease Using Adaptive Optics
A new optics technology is providing scientists with real-time microscopic images of the living retina, and may allow doctors to focus in on earlier diagnosis and treatment of diseases such as diabetes and glaucoma.
University of Houston researchers are using a technology called adaptive optics to peer inside the eyes of human subjects and for the first time get clear, sharp images of features such as bloo
Results reported in Nature Medicine
Opening up the possibility of a new approach to the treatment of diabetes, researchers have shown in animal studies that a drug long available in Europe can simultaneously block three of the major biochemical pathways responsible for the blood-vessel damage that causes serious diabetic complications.
Dr. Michael Brownlee of the Albert Einstein College of Medicine was the senior researcher for the international consortium that carried out t