New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
The answer to how the complex, cavernous inner ear forms from a mostly homogenous group of cells may be that it doesn’t, says a Medical College of Georgia researcher who has found a new cell type that appears to migrate to the developing ear.
Dr. Paul Sohal first saw the cells he named ventrally emigrating neural tube cells in 1995, following the path of newly formed nerves out of the developing neural tube.
His research published in the June issue of the International Journal of D
In Letter to Nature, NYU and Syracuse neuroscientists prove that we read by detecting simple features
Do we visually recognize things — words or faces — by wholes or by parts? Denis Pelli of New York University and Bart Farell of Syracuse University have answered that question in their forthcoming Letter to Nature. Their article, “The Remarkable Inefficiency of Word Recognition,” is accompanied by a “News and Views” piece discussing their work.
Using the example of letters
C.J. Zhong hopes that within the next three to five years diabetics the world could see their quality of life enhanced by his tiny invention-a chip-sized pump with no moving parts. The device is also expected to find its way into myriad industrial and environmental applications, where it could mean huge savings in manufacturing and monitoring processes.
Zhongs patent on the low-power, electrically driven pumping device is one of the reasons the State University of New York has broken i
The ability of proteins to guide small molecules to reaction sites and across membranes is essential to many metabolic pathways, but the process is not well understood. Now, scientists at the University of Illinois at Urbana-Champaign have shown that a globular protein with a barrel structure can direct small molecules in much the same fashion as a membrane protein.
Chemistry professor Zaida Luthey-Schulten, graduate student Rommie Amaro, and Emad Tajkhorshid, assistant director of physics
American Heart Association meeting report
For centuries, the herb Chinese gastrodine has been used in China to treat disorders such as dizziness, headache and even ischemic stroke. Research presented today at the American Heart Associations Second Asia Pacific Scientific Forum shows treatment with a gastrodine compound granule is effective in improving impaired memory, orientation, language and other effects of stroke in patients who were diagnosed with mild to moderate vascular
Humans became hairless to reduce the effects of the many biting flies and other disease-carrying parasites that live in fur and to enhance sexual attractiveness and selection, according to scientists from the Universities of Reading and Oxford. The new theory, which challenges the accepted view that human hairlessness evolved to control body temperature in hot climates, is to be published by the Royal Society in Biology Letters, a new companion to Proceedings: Biological Sciences.
Humans ar
Whether food-borne bacteria make people sick depends on a variety of factors, and better understanding of the infection process could lead to ways to stop such illnesses from occurring, according to Purdue University scientists.
In the first comprehensive study of the virulence of Listeria monocytogenes, researchers report that how well the bacteria attach to cells does not alone determine the degree of illness. The factors that determine if a person becomes ill and the degree of illness in
Scientists working with cells that may someday be used to replace diseased or damaged cells in the brain have taken neural stem cell technology a key step closer to the clinic.
Writing in the current online edition (June 2003) of the Journal of Neurochemistry, scientists from the University of Wisconsin-Madison’s Waisman Center describe the first molecular profile for human fetal neural stem cell lines that have been coaxed to thrive in culture for more than a year.
The work is a
Cells show promise for cancer and transplant patients because of rapid growth in bone marrow
Scientists with University Health Network have discovered a new class of human stem cells that rapidly grow when implanted in the bone marrow of mice. The findings, available today in an advance on-line publication of the international scientific journal Nature Medicine, are a major advancement in human stem cell research with possible significant clinical implications for designing more effec
Advanced Control Research Ltd (ACR) is developing a new microchip system that will give prosthetic arm users more movement and control of their artificial limbs thanks to an Invention & Innovation award of £65,000 from NESTA (the National Endowment for Science, Technology & the Arts), the organisation that invests in UK creativity and innovation.
The ACR system uses myoelectric technology to transfer the user’s thought processes into a range of movements. It does this by interpreting electr
Researchers have identified a mechanism by which the eight amino acid peptide NAP, an active fragment of a neuroprotective brain protein, protects against alcohol-induced embryo toxicity and growth retardation in mice. Their findings bring alcohol researchers a critical step closer to developing pharmacologic agents to prevent alcohol-induced fetal damage. The study, funded by the National Institutes of Healths National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute o
Finished sequence reveals twice as many genes, cereal similarity
Behold a grain of rice. Inside are thousands of cells; within each cell are 12 chromosomes; and on rices smallest chromosome, No. 10, are about 3,500 genes and more than 22 million base pairs, the links in the chain of DNA.
So, whats the big deal about rices smallest chromosome?
There are several, according to a report in the June 6 issue of the journal Science. Upon close exami
For decades, scientists have disagreed about the way the brain gathers memories, developing two apparently contradictory concepts. But newly published research by a team of scientists at Rutgers-Newarks Center for Molecular and Behavioral Neuroscience (CMBN) indicates that both models of memory may be partially correct – and that resolving this conflict could lead to new approaches for the treatment of memory disorders such as Alzheimers Disease.
The dispute has centered on how
Scientists announce in the current issue of the journal Nature their discovery that plants respond to environmental stresses with a sequence of molecular signals known in humans and other mammals as the “G-protein signaling pathway,” revealing that this signaling strategy has long been conserved throughout evolution. Because a large percentage of all the drugs approved for use in humans target the G-protein signaling pathway, the team’s findings could also be used in the search for plant compounds t
In plants, many proteins are degraded or activated within the vacuole, a large water and nutrient-filled vesicle found in plant cells that helps maintain the shape of plant cells and that stores food molecules. The manner by which this degradation or activation occurs, however, is uncertain.
In the June 10, 2003, issue of the Proceedings of the National Academy of Sciences (PNAS), however, scientists from UC Riverside identify a key protein, vacuolar processing enzyme or VPEg, in Arabidops
A new way to make gold form inside the cells of a micro-organism is published today in the Institute of Physics journal Nanotechnology. Researchers from the National Chemical Laboratory and the Armed Forces Medical College, both in Pune, India, have been using “green chemistry” to develop an eco-friendly way to make tiny gold particles without using toxic chemicals.
Such gold nanoparticles of uniform size can be used in labelling proteins, nucleic acids and other biomolecules, which could l