New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Chemists at Rice University have identified a chemical process for cutting carbon nanotubes into short segments. The new process yields nanotubes that are suitable for a variety of applications, including biomedical sensors small enough to migrate through cells without triggering immune reactions.
The chemical cutting process involves fluorinating the nanotubes, essentially attaching thousands of fluorine atoms to their sides, and then heating the fluoronanotubes to about 1,000 Celsi
Researchers at the University of California, San Diego (UCSD) School of Medicine have identified a previously unknown component of the body’s cellular garbage disposal called the ubiquitin system, which is responsible for regulation of cell function by removal of abnormal and unneeded proteins.
Published in the July 8, 2003 issue of Proceedings of the National Academy of Sciences, the study provides the first description of a molecule called GAIP interacting protein N terminus (GIPN)
Virginia Tech wood scientists hope that their vacuum-drying project will benefit wood pallet and container manufacturers and hardwood sawmill businesses across the nation.
“The vacuum controlling system eliminates the need for a heating system, saves energy, and does not release ozone-depleting chemicals into the earths atmosphere,” says Zhangjjng Chen, one the researchers working on the project at the Center for Unit Load and Design in the wood science and forest products depa
In a river valley just southwest of Mexico City stands a small patch of teosinte – a wild, weedy grass thought to be the ancient ancestor of corn. As a gentle breeze blows gene-carrying pollen from a nearby crop of maize to its wild relative, the genetic integrity and even survival of this ancient plant and others could be jeopardized, according to new mathematical models.
The models, described in the July 23 online edition of the Proceedings of the Royal Society of London and develo
Innovative test based on nanoshells could provide critical info for ER doctors, others
Nanotechnology researchers at Rice University have developed a new method of testing whole blood that could allow emergency room doctors and other point-of-care health professionals to rapidly diagnose a variety of ailments, including hemorrhagic stroke, heart attack, and various infectious diseases.
The test, which is faster than existing whole-blood immunoassays, uses gold nanoshells, tiny op
If your parents had coronary heart disease before age 60, the walls of your neck arteries are more likely to be thicker, putting you at higher risk of heart disease, too, researchers report in today´s rapid access issue of Circulation: Journal of the American Heart Association.
Compared with people with no parental history of early-onset coronary heart disease (CHD), those with at least one parent who had a heart attack or other coronary event such as chest pain before age 60, had th
A team of scientists – including one from Michigan State University – has announced a genomic sequence for the rest of us: mapping the DNA of a grain fungus that wreaks havoc with beer brewing.
The genomic sequence of the fungal plant pathogen, Fusarium graminearum, has been completed, providing scientists a roadmap to combating a fungus that infects wheat and barley crops, rendering them unusable.
“We have enough to do a tremendous amount of good work,” said Frances Trail,
In a study made possible by the sequencing of the human genome, scientists at the University of Illinois at Chicago have identified 57 genes involved in the growth of human tumor cells.
Some of these genes appear to be linked with the growth of cancerous cells only – not healthy cells – making them possible targets for new drugs that could halt the spread of disease without necessarily compromising normal processes.
The research relied on a strategy pioneered in the laboratory of I
A simple, quick and accurate hand-held kit which can be taken out into the field to test for toxic chemicals is being exploited by a spin-out company from the University of York.
The BATT (Bioassay Toxicity Testing) device is now being tested by environment agencies, textile industries, water boards, and diagnostic companies involved with pesticide measurement.
Microbiologist Dr Russell Grant was working on a third-year project as an undergraduate at York when the idea of th
Leading scientists worldwide investigating the cause of Severe Acute Respiratory Syndrome (SARS) confirm that a novel coronavirus is the primary cause of the disease. The study is published on THE LANCET’s website at 0001 H Tuesday 22 July UK time.
SARS was first reported in China in November 2002, with over 8300 cases and 812 deaths reported by the beginning of July 2003. A novel coronavirus has been identified as the likely cause of SARS. Albert Osterhaus from Erasmus University, R
Genotyping provides route to tailored treatment at lower cost with less side effects
A new centralised genotyping service that enables clinicians to differentiate between types of hepatitis C infections is poised to improve treatment for patients with Hepatitis C, a severely under treated viral infection in the UK. The new service, available through HepCgen will allow clinicians to tailor costly interferon-based treatment regimes to the patients’ viral genotype, thus lowering costs a
Bacteria and viruses are completely different classes of pathogens, and not surprisingly the body uses completely different molecular “receptors” to detect them in order to mount an immune defense.
Paradoxically, while the detection systems are different, the actual immune defenses the body employs to clear the system of viral or bacterial infection are much the same. As are the symptoms–to you or me, fighting off bacteria or viruses can produce the same fatigue, inflammation, or hac
Primary author of several recent studies involving di-n-butyl phthalate (DBP) and linuron (L) discusses his findings and what they mean for understanding human development.
Over the last ten years, US researchers have observed a marked increase in some male reproductive disorders, including undescended testicles, increased instances of testicular cancer, and decreased sperm count. In the last 20 years the rates for testicular cancer have grown almost five-fold in Denmark, yet neighbo
A single protein acts as a key switch point in frontline immune system reactions to both bacterial and viral infections, according to a report published online today in the journal Nature. In determining how this protein functions, a team of scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID) can now explain why certain symptoms, such as fever, occur regardless of the cause of infection.
Bruce Beutler, M.D., of The Scripps Research Institute in L
“Eighty percent of all babies born in the US that have cystic fibrosis (CF) are born to parents with no previous family history.” This attention-getting quote, used frequently by an activist in the CF community, makes it powerfully clear what few people realize: that both parents did not know they would pass on to their child the life-altering CFTR gene, the gene mutated in cystic fibrosis.
In fact, the Cystic Fibrosis Foundation estimates that more than 10 million Americans are unkno
Hand held metal detectors (HHMDs), such as those used for security checks in airports, do not cause harmful heating or nerve stimulation in pregnant women, according to research published today (22 July 2003) in the Institute of Physics journal Physics in Medicine and Biology. The role of the Center for Devices and Radiological Health (CDRH), Maryland, is to ensure the safety of radiological products, so electromagnetic wave emitting HHMDs were an obvious choice for them to investigate, especially fo