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New Insights Into Targeting Stomach Bug Virus Treatment

New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…

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Health & Medicine

Mosquito Mapping System Aims to Combat Disease Spread

Got mosquitoes? Thanks to a new Web-based mapping system, you soon will be able to see if West Nile encephalitis or some other mosquito-borne disease is in your neighborhood.

The Knowledge Engineering Lab in the department of entomology at Texas A&M University is heading up the project to develop the statewide Mosquito Spatial Information Management System. The real-time system — that will be available through the Internet — will map disease occurrence, epidemiology and control

Health & Medicine

New Insights on Heart Attack Treatment from Old Drug

Bretylium’s unique effects may point to new concept of heart attacks

An “old” drug has unique benefits for patients with acute myocardial infarction (AMI; commonly known as heart attack), a finding that may contribute to a new understanding of how heart attacks develop, according to an article in the September/October American Journal of Therapeutics.

In the definitive report, Marvin Bacaner, M.D., University of Minnesota, describes the effects of the antiarrhythmi

Health & Medicine

New Research Results: ’Heart Jacket’ Shown to Be Effective Treatment for Heart Failure

SLU Cardiologist Was First in Missouri to Investigate the Device

The concept is simple: to halt deterioration of the heart muscle, wrap it in a mesh-like net to prevent further enlargement in patients with heart failure. It’s like a jacket for the heart.

New research results from Saint Louis University and other institutions across the country found the “heart jacket” technique helped patients feel better and reduced the likelihood that they would need a heart t

Life & Chemistry

Lp-PLA2 Enzyme: New Insights into Ischemic Stroke Risk

New ARIC data confirm enzyme’s potential as a target for independent cardiovascular diagnosis and therapy

High levels of an enzyme – lipoprotein-associated phospholipase A2 (Lp-PLA2) – believed to trigger a cascade of inflammatory events in atherosclerosis can independently predict increased risk of stroke, even after accounting for both traditional and novel cardiovascular risk factors, according to a new analysis by investigators from the ongoing Atherosclerosis Risk in

Life & Chemistry

New Protein Structure Sheds Light on E. Coli Infection Pathway

New protein structure is a first step toward preventing E. coli diseases

Scientists from the U.S. Department of Energy’s Brookhaven National Laboratory and Stony Brook University have determined the two-dimensional crystal structure of a membrane protein involved in the process by which the Escherichia coli (E. coli) bacteria infects a human. This protein structure is a first step to better understanding how an E. coli infection begins, which may lead to information on how to blo

Health & Medicine

Family Meals Foster Healthy Eating Habits in Adolescents

U of MN study finds dinner table atmosphere is also important

It’s not only the routine of sitting down to dinner as a family, but the importance, structure, and atmosphere of family meals that may help steer adolescent girls from eating disorders. University of Minnesota researchers found that girls who ate regular family meals in a structured and positive environment were less likely to exhibit extreme weight control behaviors such as diet pill use, vomiting, and chronic d

Health & Medicine

Drug-Coated Stent Causes Less Inflammation, Study Finds

In the treatment of coronary artery disease, a sirolimus drug-coated stent causes less inflammation than bare metal stents, according to preliminary research presented at the American Heart Association annual meeting by Loyola University Health System, Maywood, Ill.

“Inflammatory response is a sign of advancing heart disease, so the less inflammation the better,” said lead author Dr. Fred Leya, professor of medicine/cardiology, Loyola University Chicago Stritch School of Medicine.

Health & Medicine

IgG Treatment in Pregnancy Lowers Newborn Liver Condition Risk

Treatment with high-dose immunoglobulin G (IgG) during pregnancy lessens the severity of hemochromatosis (NH), a rare, devastating gestational disease with abnormal iron accumulation in the liver and severe liver injury that almost always results in fetal death or acute liver failure in newborns.

In an article in the Nov. 6 issue of The Lancet, researchers Peter F. Whitington, M.D., and Judith U. Hibbard, M.D., described the effectiveness of treating mothers with IgG in reducing l

Health & Medicine

Pioglitazone Reduces Carotid Artery Thickness in Diabetes Patients

Changes associated with reduced risk of heart attack and stroke

Clinical study results presented today in New Orleans, Louisiana, during the American Heart Association’s Scientific Sessions 2004 proceedings, have shown that the drug pioglitazone (ACTOS®, Takeda) significantly reduced the thickness of the carotid (neck) artery in patients with type 2 diabetes. By contrast, no change in carotid thickness was seen in a group of patients who received glimepiride, an older drug for typ

Health & Medicine

Cardiac Tamponade Rates Steady Amid Clot-Busting Medications

The incidence of cardiac tamponade, an infrequent but potentially fatal event following a heart attack, has not increased despite the widespread use of clot-busting and blood-thinning medications, according to an new analysis by Duke Clinical Research Institute investigators. Since bleeding is the major side effect of such medications, researchers said concerns with increased rates of tamponade existed.

Cardiac tamponade occurs when fluids or blood fill the pericardium, the tough s

Health & Medicine

Understanding Metabolic Syndrome: Risks and Innovations

MEDIA INVITATION
Wednesday 1st December, London – Institute of Child Health

Both obesity and type 2 diabetes have become global epidemics over recent decades bringing, in their wake, a number of metabolic symptoms and cardiovascular disease risk factors. Both of these disorders, however, are just the tip of the iceberg, being just two manifestations of the metabolic syndrome (see notes) which has been suggested to affect 25% of the population in countries such as the UK and

Health & Medicine

New Insights: Innovative Treatments for Eating Disorders

Clinical eating disorders have one of the highest mortalities of any psychiatric ca tegory. They can be long lasting and life blighting. However, too often they are thought of by the general public, and sometimes even by health care professionals, either as trivial and perhaps glamorous or as rare and extraordinary.

A team of Leicester researchers is keen to correct these misconceptions and to portray eating disorders as important, serious, ordinary – and treatable. Getting better

Health & Medicine

Morphine for Chest Pain Linked to Higher Death Risk

While patients hospitalized for a heart attack have long been treated with morphine to relieve chest pain, a new analysis by researchers from the Duke Clinical Research Institute has shown that these patients have almost a 50 percent higher risk of dying.

The researchers call for a randomized clinical trial to confirm their analysis. Meanwhile, they advise cardiologists to begin treatment with sufficient doses of nitroglycerin to relive pain before resorting to morphine. In thei

Health & Medicine

Beta Blockers Boost Recovery After Cardiac Surgery

Starting beta-blocker treatment within 24 hours of cardiothoracic surgery provides significant recovery benefits according to new research in The Annals of Pharmacotherapy. Beta-blockers shortened hospital stays by 2.2 days and reduced atrial fibrillation, a dangerous heart rhythm, by 17.3%. These important findings were released early at The Annals of Pharmacotherapy’s Articles Ahead of Print (www.theannals.com) and will appear in the journal’s December print issue.

In

Health & Medicine

New Respiratory Sensor Enhances Emergency Response Capabilities

Respiratory sensor may provide new tool for emergency responders

Researchers have created a tiny device that can monitor a victim’s breathing in emergency situations by effectively shrinking an operating room machine into a small, disposable tool that can be carried to a disaster site.

NSF-supported researchers at Nanomix, Inc., in Emeryville, Calif., have created a transistor that fuses carbon nanotubes, polymers and silicon into a capnography sensor — a human

Life & Chemistry

NYU Team Unveils Enhanced Algorithm for Cancer Genome Detection

Researchers at New York University’s Courant Institute of Mathematical Sciences have developed a new algorithm that can lead to more accurate detection of cancer genes than previous versions. The algorithm, published in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), can also be applied to the multiple biomedical technologies (e.g., different kinds of micro-arrays) used to analyze cancer patients’ genomes.

Headed by NYU Professor Bud Mi

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