New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
The researchers describe their work in a paper accepted for publication in the Journal of the American Chemical Society, and posted on the journal’s Web site.Scientists have long been puzzled by nature’s ability to use cheap and plentiful building blocks – iron, nickel and sulfur – to achieve the catalytic performance seen in rare and expensive metals. In particular, two enzymes – iron-iron hydrogenase and nickel-iron hydrogenase – function as hydrogen processors, much like platinum….
Their findings could help scientists better understand genetic diseases, aging and cancer.Cells in plants, fungi, and animals—including those in the human…
When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free…
“It's been ten years since human stem cells were first cultured in a Petri dish,” says the study's leader Juan-Carlos Izpisúa Belmonte, Ph.D., a professor in…
A large number of circadian genes are expressed by organs such as the liver, whose activity needs to be precisely regulated over the course of the day. A team…
Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of…
Scientists have known for some time that biological molecules interact with one another in a similarly complex pattern. Now researchers at the Stanford…
Most such studies ignore differences between populations within a species and the interactions between species, in the interest of simplicity. An article in…
Researchers have long believed that the sleep disturbances common among the elderly often result from a disruption of the body’s circadian rhythms—biological…
“We found that adding gefinitib to standard chemotherapy was well-tolerated by patients who had already received chemotherapy or were frail,” said Dr. Argiris….
A vaccine for one of the most lethal cancers, advanced melanoma, has shown improved response rates and progression-free survival for patients when combined…
Early data suggests that a combination of temsirolimus and bryostatin may be active in patients with rare forms of renal cell cancer, which are less likely to…
Newcastle University researchers analysed a small clinical trial of losartan, a drug normally prescribed for hypertension, on 14 patients in Spain, who had…
The study evaluated 73 cases in which children younger than two years old were treated for obstructive sleep apnea through the removal of the adenoids,…
“Our study highlights the need for someone who is experiencing the symptoms of a mini-stroke or transient ischemic attack to get to an emergency room fast,”…
The latest advances in polyp detection, assessment of colorectal cancer risk, and patient sedation during colonoscopy will be presented today at Digestive…