New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Explosion in a chemical plant, fire on a dangerous goods freighter… the causes may be many. Prevention however, starts with testing the hazardous properties…
Quinine is a very commonly used anti-malarial drug, yet to this day the principal mode of quinine action against the malaria parasite is still largely unclear,…
The new protein, called Trim24, feeds p53 to a protein-shredding complex known as the proteasome by attaching targeting molecules called ubiquitins to the…
Findings from the study, which will appear June 29 in the online journal Public Library of Science Biology, provide a better understanding of plants' immune…
About half of the world's population carries Helicobacter pylori, mainly in the stomach. Most infected individuals never experience any symptoms, but around…
Inside the body, the bacteria multiply on the implant's surface and then build a slimy, protective film to shield the colony from antibiotics. According to a…
Writing in The Analyst – a journal published by the Royal Society of Chemistry – the developers report that their technique, which uses DNA hairpins attached…
Rheumatoid arthritis is the most common autoimmune disease, affecting around 1 in 100 people. It causes painful and persistent swelling in the joints that can…
Together with researchers in Canada and the USA they showed that this bradykinin receptor 1 (B1) controls the infiltration of immune cells into the CNS. When…
The finding, detailed this month in the Proceedings of the National Academy of Sciences, was a surprise, said principal investigator David Clayton, a professor…
Shinichi NakagawaInitiative Research ScientistNakagawa Initiative Research UnitRIKEN Advanced Science InstituteResearch on the function of a type of RNA called…
Cells produce thousands of proteins that are essential for life, but the proteins are of no use unless they can be delivered to the right places. Now, Ken…
The researchers mainly focus on the enzyme P450 StaP, which belongs to the cytochrome P450 enzyme family. These enzymes are involved in metabolic and…
In the bustling economy of the cell, little bubbles called vesicles serve as container ships, ferrying cargo to and from the port – the cell membrane. Some of…
The study, published in the June 26th issue of the journal Science, found that STAT3, in addition to its role in the cell nucleus regulating gene expression,…
Scientists at the Gladstone Institutes of Virology and Immunology (GIVI) have found another clue that may lead to eradication of HIV from infected patients who…
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