New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Using genetic manipulation of membrane voltage in Xenopus (frog) embryos, biologists at Tufts University's School of Arts and Sciences were able to cause…
Researchers at the Salk Institute for Biological Studies have developed a way to use patients' own cells to potentially cure sickle cell disease and many other…
On December 8, 2011, the Cluster of Excellence “Unifying Concepts in Catalysis” (UniCat) and chemical company BASF SE signed a cooperation agreement…
The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's…
Their report, published online in Gynecologic Oncology, suggests that this combination (ixabepilone and sunitinib), might offer a much needed treatment option…
Rahul Kohli and colleagues focus on cytosine, one of the four chemical “bases” that comprise the alphabet that the genetic material DNA uses to spell out…
The technology to obtain such a “transcriptome” has become accessible enough that full-scale sequencing is the preferred method for asking genetics questions. The population of Eric Morrow’s seminar “Neurogenetics and Disease” comprises mainly undergraduates who were skipping down the halls of their elementary schools when the first drafts of human genome sequences were published. When Morrow, assistant professor of biology, recently asked the class how to find the mutation behind a disease, a hand shot up in the back of the class to signal the answer: “Sequence the patient’s genome.”…
Neuropeptide Y (NPY) is the most abundant peptide hormone of the central nervous system. It is involved in various processes including stress management, the…
A vertically organized series of connected neurons that form a brain circuit, the cortical column is considered the elementary building block of the cortex,…
Serious traumatic injuries, including major burns, set off a “genomic storm” in human immune cells, altering around 80 percent of the cells' normal gene…
Not only does it affect a person's ability to concentrate and make decisions, it also alters their ability to experience pleasurable emotion, and instead…
But for most children, such behavioral therapy techniques don't work long term, according to Kerri Boutelle, PhD, associate professor of psychiatry and…
A dramatic increase in the incidence of chronic inflammatory diseases such as asthma, allergy, and irritable bowel syndrome, has led to concern about how…
Because PrEP is based on the same drugs used to treat HIV-infected individuals, the big public health fear is that the dual use of these drugs will lead to…
They can be collected from routinely collected fluids such as blood, saliva, and urine. However, a number of factors can interfere with the accuracy of miRNA…
Jerome Baudry and Yinglong Miao, who are jointly affiliated with ORNL and the University of Tennessee, have performed simulations to observe the motions of…
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