New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
Arun Bhunia, a professor of food science; Mary Anne Amalaradjou, a Purdue postdoctoral researcher; and Ok Kyung Koo, a former Purdue doctoral student, found…
Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy “bait” is a greater…
A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70),…
30 years ago, in June 1981, two doctors, Michael Gottlieb and Wayne Sandera of the University of California in Los Angeles, described the very first AIDS cases…
When the outbreak of Legionnaires' disease was detected among eight people in southeast Wisconsin, state and local public health officials worked closely with…
Most proteins have multiple moving parts that rearrange into different conformations to execute particular functions. Such changes may be induced by molecules…
The mammalian gut is home to hundreds of bacterial species that contribute to food digestion and, in some cases, inflammatory gut diseases. Probiotics,…
In mouse, odor is sensed by the main olfactory epithelium (MOE) by about 1100 types of olfactory receptors that are expressed by olfactory sensory neurons….
A molecular mechanism that links diet, obesity and diabetes involves depletion of specialized ‘transporter proteins’, a Japanese–American team has found1….
Much of the work was done at the Jan and Dan L. Duncan Neurological Research Institute at Texas Children's Hospital. MeCP2 is a “Goldilocks” in the protein…
Persilastaffanes are an unusual new class of compounds that are introduced in the journal Angewandte Chemie by Japanese researchers led by Takeaki Iwamoto at…
Much of what living cells do is carried out by “molecular machines” – physical complexes of specialized proteins working together to carry out some biological…
The findings will be published online January 8 in the journal Nature Chemical Biology. MPS is caused by the absence or malfunctioning of a lysosomal enzyme…
A registry -which includes every patient in Sweden having percutaneous coronary intervention (PCI) for the treatment of acute and stable coronary artery…
The consequences of delaying effective hypertension treatment for up to a year were small—a two-day reduction in quality-adjusted life expectancy—according to…
This is what a new study from Lund University in Sweden has found.Physician Oskar Hansson and his research group are studying biomarkers – substances present…