New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
They show extremely high gene transfer efficiency and afterwards enable the quick and simple separation of the transfected cells from the transfection pool. A…
From a purely intuitive point of view, it is easy to believe that our ability to actively pay attention to a target is inextricably connected with our capacity…
For their analysis, computational bioinformatics researchers at the Cluster of Excellence “Multimodal Computing and Interaction” at Saarland University…
Researchers at the Medical Research Council (MRC) Centre for Regenerative Medicine at the University of Edinburgh have discovered how to enhance the production…
The placental niche, a stem cell “safe zone,” supports blood stem cell generation and expansion without promoting differentiation into mature blood cells,…
The study proposed a new model to explain how mammalian cells establish the sense of direction necessary to move, as well as the mechanism that a…
Their report on the new NOSH-aspirin, so named because it releases nitric oxide (NO) and hydrogen sulfide (H2S), appears in the journal ACS Medicinal Chemistry…
The winter sun feels welcome, but not so a summer sunburn. Research over the past 20 years has shown that proteins on the surface of nerve cells enable the…
The study, in which mice were bred to make a supercharged version of the protein focal adhesion kinase, or FAK, appeared March 1 in the online edition of the…
Three of the genes are particularly intriguing because they code for proteins similar to those known to regulate mammalian embryonic stem cells. Such genetic…
Even in the early stages of cancer, individual cancer cells can be found in the blood. Certain subsets of these circulating tumor cells can cause metastasis. In cases of breast cancer, it is known that these cells can differ from the original tumor cells, which allows them to survive treatment to cause later recurrence. It could thus be quite informative to detect these cells in the blood and examine them more closely. In the journal Angewandte Chemie, researchers at the University of Washington (Seattle, USA) describe a new chip-based method that allows for the detection and isolation of tiny concentrations of such cells in blood. …
The work focused on sulfa drugs and their target enzyme, dihydropteroate synthase (DHPS). Most disease-causing microorganisms need DHPS to help make the…
In the report, the researchers describe the case of a 32-year-old man who wasn't wearing a helmet when his all-terrain vehicle crashed. Initially, his CT scans…
According to a study just published in the American Journal of Obstetrics and Gynecology this measure prevented childhood lead poisoning and reduced the…
Researchers at Emory University School of Medicine and Atlanta Veterans Affairs Medical Center have been investigating memory-building strategies for people…
The new research, available online and published in the March 1 issue of the Journal of Clinical Investigation, was carried out in the laboratory of Dr. Joseph…