A collaboration between scientists at UCLA, Caltech, Stanford, Siemens and Fluidigm have developed a new technology using integrated microfluidics chips for simplifying, lowering the cost and diversifying the types of molecules used to image the biology of disease with the medical imaging technology, Positron Emission Tomography (PET). These molecules are used with PET to diagnostically search throughout the body to look for (image) the molecular errors of disease and to guide the development of
“4D ecography may well be a significant advance in the prenatal diagnosis of congenital cardiopathy”, explained Dr. Juan Luis Alcázar, specialist at the Obstetrics and Gynaecology Department of the University Hospital (University of Navarre).
One of the most recent novelties in ecographic studies has been the application of a fourth dimension, i.e. movement added to three-dimensional reconstruction. According to Dr. Alcázar, “the development of the STIC system, carrying out the
By comparing these two functional images, physicians may be able to better diagnose and treat patients with brain disorders
Philadelphia, PA) – Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brains function concurrently. This analysis could lead to better diagnosis and treatment in patients suffering from brain disorders, like Alzhe
At first glance airplane wings and human hearts have little in common, but, say a team of European researchers, a technology used to measure airflow over wings can now be used to help keep hearts in working order.
The researchers optimised a Particle Image Velocimetry (PIV) system traditionally used to improve the aerodynamics of aircraft wings to make it capable of accurately measuring the effects of medical implants on blood flow. Their work will allow medical device manufactu
A computer-aided detection system not only helps radiologists detect more breast cancers, but also helps detect smaller tumors in younger women, a new study shows.
The study included 27,274 screening mammograms done over a three year period—19,402 were done using a computer-aided mammography detection system (CAD); 7,872 were mammography studies done before the CAD system was installed, said Tommy E. Cupples, MD of ImageCare, LLC in Columbia, SC, and the lead author of the study.
Scientists at the University of Liverpool have found a way of identifying families at high risk of pancreatic cancer.
The team has developed a novel means of testing for pancreatic cancer that will enable doctors to treat the killer disease at its earliest stages. They are also now able to show how the risk of cancer for these patients changes with age.
The Liverpool-based study group known as EUROPAC (European Registry Of Hereditary Pancreatitis And Familial Pancreat
Preliminary results from a large, clinical trial of digital vs. film mammography show no difference in detecting breast cancer for the general population of women in the trial. However, those women with dense breasts, who are pre- or perimenopausal (women who had a last menstrual period within 12 months of their mammograms), or who are younger than age 50 may benefit from having a digital rather than a film mammogram. The results were reported September 16, 2005 in a special online publication
Tool quantifies level of consciousness, severity of brain injury
Mayo Clinic neurologists have created the first new, reliable and easy-to-use clinical tool in 30 years for measuring coma depth, a proposed replacement for the Glasgow Coma Scale. The new scoring system, called the FOUR (Full Outline of UnResponsiveness) Score, will be described in the October issue of Annals of Neurology, to be published online Friday, Sept. 9.
When using the FOUR Score, evaluators a
3D MRI can detect pancreatic cancer when it is smaller and patients have a greater likelihood of survival, a new study shows.
The study included 57 patients who had clinical symptoms of pancreatic cancer. All had contrast enhanced 3D gradient-echo MRI examinations. Radiologists correctly identified pancreatic cancer in 24 patients, said Richard Semelka, MD, professor of radiology, at the University of North Carolina, Chapel Hill, and an author of the study. Eight of the cancers fo
A temporary under-the-skin sensor could monitor a variety of health indicators for soldiers, athletes, diabetics, infants, and critically ill patients without wires and at a distance, according to a team of Penn State chemical engineers.
“We were asked to develop micro sensors for metabolic monitoring of troops,” says Dr. Michael Pishko, professor of chemical engineering and materials science and engineering. “These implantable sensors are intended to monitor the physiology of t
Although minimally invasive prostate removal aided by a robot can lead to less blood loss, shorter hospital stays and fewer complications, there is no evidence that the procedure improves cure rates, according to a new technology assessment.
In addition, robotic surgery, in high demand among patients, can lose money for hospitals because of its expense and special training required, according to the new review of studies by ECRI.
ECRI is a nonprofit health services res
Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans: Joslin recruiting for new Imaging in Diabetes Clinical Trial
A key obstacle to early detection of type 1 diabetes – as well as to rapid assessment of the effectiveness of therapeutic intervention – has been the lack of direct, non-invasive technologies to visualize inflammation in the pancreas, an early manifestation of disease. Instead, clinicians have had to await overt symptoms before
Johns Hopkins researchers have, for what is believed to be the first time, used a magnetic resonance imaging (MRI) technique called diffusion-weighted MRI (DWI), a technique that images the movement, or diffusion, of water molecules in tissues, to successfully determine the effectiveness of high-intensity focused ultrasound for treating uterine fibroids. Uterine fibroids are noncancerous tumors that line the uterine wall and can cause intense pain and bleeding. The study appears in the July edi
A Penn State researcher is part of the team that developed techniques that have generated insights into dietary divergences between some of our human ancestors, allowing scientists to better understand the evolutionary path that led to the modern-day diets that humans consume. “Our new techniques are allowing us to get beyond simple dichotomies and helping us understand the processes by which dietary evolution is working,” said Peter Ungar, professor of anthropology at the University of Arka
UCB today announced positive results for the two pivotal Phase III trials (PRECISE 1 and 2) of certolizumab pegol (CDP870) in the induction and maintenance of clinical response in moderate to severe active CrohnTMs disease. The PRECiSE trials assessed the safety and efficacy of CIMZIATM compared to placebo over a 26 week period, in a total of 1330 patients with active CrohnTMs disease.
Data from PRECiSE 1 and 2 will be presented in more detail at the major forthcoming gastroent
Scientists from the Flanders Interuniversity Institute for Biotechnology (VIB) associated with the University of Antwerp have achieved a new breakthrough in their research on the origins of Alzheimer’s disease. Their alternative approach opens up new prospects for developing a treatment which can slow the disease’s progress. The researchers have shown that ´the plaques´ which form in the brain of patients are linked to damage to nearby blood vessels. Leakage appears to occur between the blood vesse