… eco-friendly reactor converts air and water into ammonia. Producing enough ammonia to feed the world comes with a large carbon footprint;. process described in new UB-led study could help fix that. There’s a good chance you owe your existence to the Haber-Bosch process. This industrial chemical reaction between hydrogen and nitrogen produces ammonia, the key ingredient to synthetic fertilizers that supply much of the world’s food supply and enabled the population explosion of the last century. It may also…
Academic and industry scientists collaborate on a new method to characterize research antibodies. Structural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80 per cent of global renewable antibody production, have developed and standardized an Open Science platform to characterize research antibodies. This platform, designed to evaluate antibody specificity, aims to tackle a critical challenge in biomedical research reproducibility. Their approach was published in Nature…
Insights from the first global appraisal of microbiomes in earth’s subsurface environments. Which microbes thrive below us in darkness – in gold mines, in aquifers, in deep boreholes in the seafloor – and how do they compare to the microbiomes that envelop the Earth’s surfaces, on land and sea? The first global study to embrace this huge question, conducted at the Marine Biological Laboratory (MBL), Woods Hole, reveals astonishingly high microbial diversity in some subsurface environments (up to 491 meters…
Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, the Faculty of Medicine at Kiel University, and the Leibniz Institute of Virology in Hamburg are jointly receiving funding of nearly one million euros as part of the “Leibniz Cooperative Excellence” program. The goal of the project is to unravel fundamental mechanisms of two-pore domain potassium channels (K2P channels) – with potential new therapeutic approaches for cancer, autoimmune diseases, infectious diseases, central nervous system disorders, and cardiovascular diseases. Two-pore domain potassium channels (K2P…
Discovery could lead to new treatments for blood cancer patients currently facing limited options. Scientists at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have collared a tricky culprit that helps cancer cells evade CAR T cell therapy. CAR T cell therapy harnesses the immune system to seek out and kill…
UO researchers unravel the mechanism behind an unpleasant symptom of digestive problems. After a meal of questionable seafood or a few sips of contaminated water, bad bacteria can send your digestive tract into overdrive. Your intestines spasm and contract, efficiently expelling everything in the gut — poop and bacteria alike. A new study from the University of Oregon shows how one kind of bacteria, Vibrio cholerae, triggers those painful contractions by activating the immune system. The research also finds a…
… by turning on a protein that halts immune response. Researchers have also found that blocking the protein reactivates immune cell function, restoring the effectiveness of vaccines in an animal model. Staphylococcus aureus (S. aureus) is a major cause of skin and soft tissue infections that can sometimes lead to sepsis and toxic shock syndrome. The microbe poses a significant threat to public health, made worse by the spread of methicillin-resistant Staphylococcus aureus bacteria (MRSA) in recent years. According to…
Parahydrogen-enhanced magnetic resonance spectroscopy visualizes the process of [Fe]-hydrogenase catalysis. Microorganisms have long used hydrogen as an energy source. To do this, they rely on hydrogenases that contain metals such as nickel or iron in their catalytic center. In order to use these biocatalysts for hydrogen conversion, researchers around the world are working to understand the details of the catalysis process. A team from three Max Planck Institutes (MPI), the Center for Biostructural Imaging of Neurodegeneration (BIN) at the University…
Oregon State University researchers have synthesized new molecules able to quickly capture significant amounts of carbon dioxide from the air, an important tactic in climate change mitigation. The study, which focused on titanium peroxides, builds on their earlier research into vanadium peroxides. The research is part of large-scale federal effort to innovate new methods and materials for direct air capture, or DAC, of carbon dioxide, produced by the burning of fossil fuels. Findings of the research, led by May Nyman and…
Arrayed tungsten disulfide nanotubes pave way for new tech applications. Researchers from Tokyo Metropolitan University have made tungsten disulfide nanotubes which point in the same direction when formed, for the first time. They used a sapphire surface under carefully controlled conditions to form arrayed tungsten disulfide nanotubes, each consisting of rolled nanosheets, using chemical vapor deposition. The team’s technique resolves the long-standing issue of jumbled orientations in collected amounts of nanotubes, promising real world device applications for the exotic anisotropy…
… reversible sliding motion in ammonium-linked ferrocene. Researchers stabilized ferrocene molecules on a flat substrate for the first time, creating an electronically controllable sliding molecular machine. Artificial molecular machines, nanoscale machines consisting of a few molecules, offer the potential to transform fields involving catalysts, molecular electronics, medicines, and quantum materials. These machines operate by converting external stimuli, like electrical signals, into mechanical motion at the molecular level. Ferrocene, a special drum-shaped molecule composed of an iron (Fe) atom sandwiched between…
Supramolecular chemistry: Publication in Angewandte Chemie. How can aromatic compounds be separated from so-called aliphatic compounds efficiently without having to rely on energy-intensive processes? In the scientific journal Angewandte Chemie (Applied Chemistry), chemists from Heinrich Heine University Düsseldorf (HHU) present an innovative molecular sieve made of partially fluorinated macrocycles that can separate these compounds selectively. Aromatic compounds – substances with flat, ring-shaped structures made up of carbon atoms – play an important role in organic chemistry. Among other things, they…
Foundation for new cancer treatment strategies. A team led by researchers at the Technical University of Munich (TUM) has, for the first time, grown tumor organoids – three-dimensional miniature tumors in the laboratory – that mimic the different structures and characteristics of pancreatic cancer. The scientists investigated how the various tumor organoids react to established and novel treatments. This opens the door to the development of effective new therapies. Pancreatic cancer ranks among the most lethal cancers, with an exceptionally…
The development of molecules to study and treat disease is becoming increasingly burdened by the time and specificity required to analyze the vast amounts of data generated by synthesizing large collections of new molecules. Scientists at St. Jude Children’s Research Hospital present a novel solution to this problem, using the fundamental fragmentation patterns of chemical building blocks to barcode reactions from starting materials to products. In doing so, they have removed a key bottleneck in the process of synthesizing and screening small…
Carl Zeiss Foundation sponsors InteReg project at Mainz University. Collaborative project involving Johannes Gutenberg University Mainz, the Max Planck Institute for Polymer Research, and the Leibniz Institute for Resilience Research will receive EUR 6 million. The Carl Zeiss Foundation is contributing EUR 6 million to a research project on the regeneration of the nervous system at Johannes Gutenberg University Mainz (JGU). The new Interactive Biomaterials for Neural Regeneration (InteReg) project will bring together researchers from the fields of neurobiology, neuroimmunology,…
Bio-based adhesives for industrial applications. Folding boxes are considered sustainable packaging solutions for numerous everyday products – whether breakfast cereals, electronics, medicines, or perfumes. Made from paper and cardboard, folding boxes are resource-efficient in production, biodegradable, and easily recyclable. However, environmentally friendly adhesives are still lacking for completely sustainable manufacturing. Researchers at Fraunhofer Institute for Applied Polymer Research IAP are developing and testing bio-based adhesives for the industrial production of folding boxes in the project Sustainable Gluing With Renewable Adhesives…
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