Life & Chemistry

Life & Chemistry

Chemistry reveals mummies’ secrets

Ancient embalming not to be sniffed at.

Archaeologists thought they had mummification wrapped up. But a new analysis of ancient Egyptian embalming suggests that they have underestimated this sophisticated funerary practice.

Pharaonic undertakers used a wealth of oils, waxes and fats, say Stephen Buckley and Richard Evershed at the University of Bristol, UK. They are the first to study several mummies from different periods using modern analytical chemistry 1

Life & Chemistry

Sequencing Salmonella: Uncovering Typhoid and Food Poisoning Insights

Bugs behind typhoid and food poisoning give up genetic secrets.

Two teams have sequenced the genomes of two Salmonella bacteria. One is responsible for typhoid; the other causes food poisoning.

The genomes should lead to new ways to diagnose, treat and vaccinate against both diseases. Comparing the sequences should also clarify why the closely related bugs behave quite differently.

The two strains are called Typhi and Typhimurium. Typhi, the typhoid bug, infects onl

Life & Chemistry

Anthrax Insights: New Research and Bioweapons Focus

Recent events have confirmed that bioterrorism is no longer a threat but a reality. To provide wide-ranging access to the latest scientific information about anthrax and other potential bioweapons, Nature has put together a special online focus on this issue. This focus includes the pre-publication* of two research papers on anthrax toxin, as well as a collection of research, news and feature articles from our electronic archive. Because of the heightened interest in this area, among both the scient

Life & Chemistry

Fluorescent Daisies: Genetic Engineering for Luminous Blooms

Genetic engineering gives us the fluorescent daisy.

It’s produced in Italy and guaranteed to make the face of that special someone light up. It’s the luminous bouquet. Under ultraviolet light the apparently normal blooms glow an unearthly green.

“The fluorescent flowers show that genetic engineering can be developed just for beauty,” says their developer, Tito Schiva of the Experimental Institute of Floriculture, San Remo. The technique should work for any white flower, Sch

Life & Chemistry

Meat fuelled Midas’ rot

The gold-loving king’s rich diet may have hastened his decay.

Legend says that lust for gold was the cause of King Midas’ downfall. But his appetite for meat may have destroyed the final monument to his greatness 1 .

A mound excavated 44 years ago in Turkey is thought to be the resting place of the eighth-century BC ruler of Phrygia. The large tomb, although built of durable cedar wood, is in surprisingly bad shape, says geophysicist Timothy Filley of the Car

Life & Chemistry

Flies caught napping

Researchers discover two molecules that help fruitflies sleep.

Mutant flies that lack the chemicals sleep more. In mammals the same molecules are also involved in learning and memory, supporting the idea that one function of sleep is to consolidate our record of the day’s experiences 1 .

The molecules are cyclic AMP and CREB, chemical messengers that work within cells. Cyclic AMP activates CREB, which then switches on genes.

Joan Hendricks, of th

Life & Chemistry

Computers Uncover Protein Functions Through Shape Analysis

Two techniques may help deduce proteins’ functions.

Imagine trying to guess what machines do just be looking at them. Even a can-opener would pose problems, if you didn’t know about cans. This is the challenge that faces molecular biologists as they try to make sense of protein molecules in the cell.

Two new techniques may help. One deduces a protein’s function from its shape; the other deduces its shape from a list of component parts 1 , 2 .

Life & Chemistry

ATTO-TEC® Stable activated fluorescent dyes at room temperature (RT)

ATTO-TEC® has developed the second generation of fluorescent dyes which are stable at room temperature for more than six months.

With Atto 520, Atto 565 and Atto 590 we are pleased to offer three stable fluorescent dyes as amine-reactive succinimidyl esters which will be available from November 2001 on. This allows researchers an easy handling for selectively target- labeling by linking a fluorophore to primary amine groups on proteins or modified nucleic acids.
Further stable activate

Life & Chemistry

Chemists Innovate Automated Synthesis of Complex Molecules

Chemists build molecules by paring them down

Complex molecules, such as many drugs, can be fiddly to assemble. By binding their starting compounds in chains 1 , chemists in Denmark may have found a way speed the automated chemical synthesis of such complicated products.

Les Miranda and Morten Meldal of Carlsberg University in Copenhagen have solved the following problem. Complex molecules are usually built up from a core with several near-identical hooks on w

Life & Chemistry

Oral flex – Chameleon tongues have special muscle to haul in dinner

Chameleons can reel in prey anywhere within two-and-a-half body lengths of their jaws. Their tongues can overcome even a bird’s weight and reluctance to be eaten. How? Muscles that are unique among backboned animals, researchers now reveal.

Anthony Herrel of the University of Antwerp, Belgium, and colleagues put crickets at different distances from the noses of two chameleon species, Chameleo calyptratus and Chameleo oustaletti. The tongues of these 12-cm-long reptiles pull at maximum stren

Life & Chemistry

Bacteria Inspire Chemists to Create Clean Hydrogen Fuel

Chemists copy bacterial tricks for making clean fuel.

Bacteria are teaching chemists their tips for creating lean, green fuel. US researchers have developed a catalyst based on a bacterial enzyme that converts cheap acids to hydrogen, the ultimate clean power source.

Unlike other fuels, hydrogen is non-polluting: its combustion makes only water, instead of greenhouse gas carbon dioxide or the poison carbon monoxide. Thomas Rauchfuss and colleagues at the University of Illino

Life & Chemistry

Unlocking Chromosome Secrets: Centromere Code Revealed

Sequencers expose secret chromosome centre.

February’s celebrations hid a dark secret: the human genome sequencers hadn’t touched the hearts of our chromosomes. Now, at last, one chromosome’s inscrutable midpoint, its centromere, has given up its genetic secrets.

Centromeres look like the ’waist’ in an X. They share out chromosomes fairly when a cell divides. Defective centromeres may underlie many cancers, in which problems with chromosome movement

Life & Chemistry

Barcoded Metal Rods: A New Way to Track Molecule Interactions

Stripes help chemists shop for molecules.

Scientists may soon be sticking bar-coded metal rods into molecules to see what they do in a crowd 1 . The rods could help to track the functions and interactions of genes, and may aid drug discovery.

At only a few thousandths of a millimetre long, the rods are small enough to fit inside a single red blood cell. Christine Keating, of Pennsylvania State University, and colleagues cast them inside cylindrical pores in a

Life & Chemistry

Gene Therapy Boosts Male Bonding in Voles and Beyond

Spells and incantations step aside: scientists have found a genetic elixir of love. It makes males more faithful to females and more friendly to fellow males. It could also shed light on bonding disorders such as autism.

Larry Young of Emory University in Georgia and colleagues used a virus to deliver a gene straight to the part of voles’ brains responsible for rewards and addiction, the ventral pallidum. The gene made the animals’ brains more receptive to the hormone vasopressin 1

Life & Chemistry

Squirrel Migration: How Forestry Shaped Their Genetics

Museum exhibits’ genes record British forestry policies

Commercial forest planting in the north of England drew red squirrels westwards in the 1980s say UK researchers. This migration led to big changes in squirrel numbers and genetics.

The finding has implications for the protection of the endangered red squirrel (Sciurus vulgaris). Many conservationists advocate leaving ’wildlife corridors’ for animals to travel between patches of fragmenting habitat. This is the first evi

Life & Chemistry

Fossils Reveal Land Mammals’ Link to Ancient Whales

Fossils bridge gap between land mammals and whales.

Fifty million years ago, two mammals roamed the desert landscapes of what is now Pakistan. They looked a bit like dogs. They were, in fact, land-living, four-legged whales.

Their new-found fossils join other famous missing links, such as the primitive bird Archaeopteryx , that show how one group of animals evolved into another. And they undermine the two prevailing theories about which land mammals are most closely re

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