Research team from Italy makes presentation on project at Congress of Neurological Surgeons Annual Meeting
A team of neurosurgeons and scientists from Italy is looking into whether stem cells derived from a brain tumor patient’s own skin can be used to fight the tumors. The researchers successfully grew stem cells from skin samples of adult patients with brain tumors. It is hoped that these cells can then be used as a new brain tumor therapy, which has been attempted successfully
Research team from cleveland makes presentation on findings at Congress of Neurological Surgeons annual meeting
It had long been thought that once the human brain is fully matured, no new brain cells develop. Now a team of researchers and scientists has found evidence of cell generation in the brains of adults with epilepsy and say it could lead to ground-breaking treatment for the disease. William Bingaman, M.D., a neurosurgeon from the Cleveland Clinic, presented his findings at
Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered the gene for a form of Joubert Syndrome, a condition present before birth that affects an area of the brain controlling balance and coordination in about 1 in 10,000 individuals. Their study, published in the November 2004 issue of the American Journal of Human Genetics*, pointed to mutations in a gene called AHI1 that lead to the production of a protein the scientists named Jouberin.
Soda, Halloween candy and other food products that contain high-fructose corn syrup and other sweeteners could one day get a fresh makeover using honey, one of the most ancient sweeteners, researchers say.
Scientists at the University of Illinois at Urbana-Champaign say that honey may be a healthier alternative than corn syrup due to its higher level of antioxidants, compounds which are believed to fight cancer, heart disease and other diseases.
Honey, which contains a
Forensic genetics is the branch of genetics that, through DNA analysis and comparison, deals with the resolution of legal problems such as paternity tests. Recently, it has been proposed that single nucleotide polymorphisms (SNPs) could be used as a new genetic marker in the field eventually even replacing the methods/markers now employed. But in an article just published online in Forensic Science International, a team of scientists challenges the effectiveness of SNPs in kinship studies predic
Its two-step handiwork described in The EMBO Journal as most efficient of any enzyme
A newly discovered enzyme described by University of Pittsburgh researchers in a study published online today, is believed to play a key role in maintaining the integrity of a cell’s genetic information – the basis by which the life of a cell or species is preserved – by allowing its DNA to be replicated despite discovery of a mishap on the sequence that it corrects with a new mistake. Its sop
A common antibacterial and antifungal ingredient used in mouthwashes and tooth paste may have another positive medicinal use: protection against skin cancer.
According to new studies, sanguinarine was shown to enhance production of proteins that induce cell death, or apoptosis, in cells damaged by ultraviolet-B (UVB) radiation. The alkaloid also restricts skin cell production of other pro-proliferation proteins. “This natural compound may protect skin from cells that acquire the
Researchers have uncovered a specific signaling mechanism that contributes to the development of colorectal cancer, one of the most common deadly human cancers. The discovery furthers the understanding of mechanisms that contribute to disease progression and provides new avenues for development of therapies for colorectal cancer.
According to study author, Dr. Marcus F. Neurath from the University of Mainz in Germany, “Several lines of evidence support an important role of TGF-b
By knocking out a single gene in mice, immunologists at Duke University Medical Center have mimicked a little-understood autoimmune disorder in humans. In the puzzling disorder, called Sjögren’s syndrome, the person’s tear and salivary glands are affected, causing dry eyes and mouth, as they are damaged by an attack of the person’s own immune cells.
According to researchers, the achievement not only offers insight into Sjögren’s syndrome, but into the genera
Diabetics could face a higher risk of both pancreatic and liver cancer, according to a Université de Montréal researcher who will be presenting her team’s findings at the Frontiers in Cancer Research Prevention Meeting. While the association between diabetes and both pancreatic and liver cancer has been previously documented, the researchers accounted for many factors unavailable in previous studies, making this the most accurate association ever found between diabetes and the incidence of live
Dolphin Quest enlists University of Pittsburgh specialist to develop custom ’scaffold’ for tissue’s repair; ’Liko is one lucky dolphin’
An expert team of marine mammal veterinarians, medical researchers, cosmetic surgeons and dolphin trainers recently joined forces to apply the latest advances in human regenerative medicine in an attempt to restore a bottlenose dolphin’s damaged dorsal fin.
The procedure on Liko, a three-year-old male dolphin
St. Jude/Johns Hopkins discovery suggests that manipulating levels of Lag-3 protein on T regulatory cells might prevent autoimmune diseases or amplify immune system attacks on cancer cells
The discovery that the Lag-3 gene acts as a brake to prevent immune system responses from running out of control solves a mystery that has puzzled researchers since the gene was discovered 14 years ago. A report on this discovery, from investigators at St. Jude Children’s Research Hospital a
Researchers have discovered an unexpected role as a tumor promoter for a molecule that was previously thought to function exclusively as a cancer suppressor in neuroblastoma (NB), a highly aggressive and deadly childhood cancer. The study, published in the October issue of Cancer Cell, reveals new evidence about what stimulates progression of neuroblastoma and may provide a likely target for new anti-cancer therapies.
Neurotrophin tyrosine kinase receptor type I (TrkA) responds to nerve
Method may help halt A-T, cancer, other genetic diseases
UCLA scientists have devised a novel way to repair one of the genetic mutations that cause ataxia-telangiectasia, (A-T), a life-shortening disorder that devastates the neurological and immune systems of one in 40,000 young children. Reported Oct. 18 in the Proceedings of the National Academy of Sciences, the findings could hold far-reaching implications for treating A-T, cancer and other genetic diseases.
Often mi
Comprehensive study raises questions about ’demethylation’ agents
Agents believed to selectively “restart” genes that limit cancer’s growth — a potential treatment option already in early clinical studies — instead turn off as many genes as they turn on, a team of researchers from the National Cancer Institute and Johns Hopkins has discovered. “We don’t know what effect all these changes might have, but it’s clear that when scientists are looking onl
Transplantation of human brain cells corrected involuntary muscle spasms in rats with ischemic spinal cord injury, according to research published online October 12 and in print October 19, 2004 in the European Journal of Neurosciences by investigators at the University of California, San Diego (UCSD) School of Medicine.
Ischemic spinal cord injury, caused by reduced blood flow to the spinal cord, occurs in 20 to 40 percent of the several hundred patients each year in the U.S. wh
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