Life & Chemistry

Life & Chemistry

Innovative Brain Tumor Treatments at MD Anderson Center

Brain tumor specialists at The University of Texas MD Anderson Cancer Center are poised on the brink of a new era

M. D. Anderson: Setting the Benchmark in Brain Tumor Treatment
Promising chemo, therapeutic viruses, cutting-edge surgery debut at Brain Tumor Center
Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

The molecular revolution that has led to improvements in treating other cancer typ

Life & Chemistry

California’s Butterflies Face Worst Year in Decades

Cold, wet conditions early in the year mean that 2006 is shaping up as the worst year for California’s butterflies in almost four decades, according to Art Shapiro, professor of evolution and ecology at UC Davis.

That’s a turnaround from last spring, when millions of painted lady butterflies migrated through the Central Valley. But other species have seen steep declines in recent years and could disappear from the region altogether.

“It has been the worst

Life & Chemistry

Genetic Breakthroughs Illuminate Retina Growth and Eye Cancer

St. Jude investigators discover role of several key genes in retina development

Investigators at St. Jude Children’s Research Hospital have discovered the role of several key genes in the development of the retina, and in the process have taken a significant step toward understanding how to prevent or cure the potentially deadly eye cancer retinoblastoma. Retinoblastoma is the third most common cancer in infants after leukemia and neuroblastoma (nerve cancer). Retinoblastoma tha

Life & Chemistry

Selective Signal Blocking May Shield Mice From MS Effects

A new way to preserve the cells that surround and protect nerves could lead to new treatments for demyelinating diseases such a multiple sclerosis, a research team reports in the May 10, 2006, issue of the Journal of Neuroscience.

The approach grew out of a novel explanation, quickly gaining followers, for the mechanism of nerve damage caused by multiple sclerosis. Instead of concentrating on the alterations that result in autoimmune assaults on the nervous system, researchers l

Life & Chemistry

NYU Algorithm Boosts Detection of Lung Cancer Genes

Researchers at New York University’s Courant Institute of Mathematical Sciences have developed a new algorithm that enhances the ability to detect a cancer gene, and have applied their algorithm to map the set of tumor-suppressor genes involved in lung cancer. The algorithm uses data from Affymetrix’s gene-chips that can scan hundreds of patients’ genomes to find gains and losses in gene-copies. The findings will appear in the July issue of the American Journal of Human Genetics.

The

Life & Chemistry

Undersea Habitat Study: Teamwork Insights for Space Missions

In isolated environments, astronauts, flight crews, offshore workers and military forces must maintain vigilance and work together to ensure a safe and successful mission.

Between daily living, telemedicine activities and moon-walking simulations, participants in the NASA Extreme Environment Mission Operations (NEEMO) 9 project helped National Space Biomedical Research Institute (NSBRI) researchers study performance ability, problem-solving and team cohesion issues that could aff

Life & Chemistry

Tracking Tumors: Insights from IFOM-IEO Cancer Meeting

2nd IFOM-IEO Campus Meeting on Cancer

What is the best strategy to determine the specific function of a gene? Certainly a good idea is to eliminate the gene and see what kind of effects this move has on the whole organism. With this goal in mind, the Dana-Farber Cancer Institute in Boston, the Whitehead Institute and the Broad Institute at MIT and Harvard – together with a consortium of five bioinformatics companies (Bristol-Myers, Novartis Pharma, Eli Lilly, Sigma, Astra Zeneca

Life & Chemistry

New Insights on Sugar’s Role in Cell Communication

A research team from Uppsala University has uncovered an entirely new mechanism for how communication between cells is regulated. By functioning like glue, a certain type of sugar in the body can make cell communication more effective and stimulate the generation of new blood vessels. The discovery paves the way for the development of drugs for cancer and rheumatism, for example. The study is being published on May 9 in the prominent journal Developmental Cell.

Blood vessels are made up o

Life & Chemistry

Scientists from the UJI use computational chemistry methods to know …

… about the nature of reactions in living beings and to be able to inhibit or accelerate them

Experimental methods have certain limits and there are times when nature briefly switches off the lights on scene to hide its tricks. One of these moments takes place during chemical reactions. All chemical reactions go through a sort of Limbo, a ghost-like stage between the initial reagents and the final product in which it is almost impossible to know experimentally what has occurred

Life & Chemistry

Novel Enzyme Sheds Light on Male Hormone Regulation

UNC scientists’ findings have implications for prostate cancer

For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.

The findings, published today (May 5) in the journal Cell, also show that the new protein plays a role in gene activation mediated by androgen receptor, a protein that re

Life & Chemistry

No-Mow Grass: A Greener Future for Your Lawn

For anyone tethered to a lawnmower, the Holy Grail of horticultural accomplishment would be grass that never grows but is always green.

Now, that vision of suburban bliss—and more—seems plausible as scientists have mapped a critical hormone signaling pathway that regulates the stature of plants. In addition to lawns that rarely require mowing, the finding could also enable the development of sturdier, more fruitful crop plants such as rice, wheat, soybeans, and corn.

Life & Chemistry

New Cell Mechanism Discovered: RHA’s Role in Protein Control

Researchers here have discovered a new mechanism used by cells – and manipulated by retroviruses – to control the making of certain essential proteins, including some involved in cancer.

The mechanism uses an enzyme called RNA helicase A (RHA), which is made by the cell.

The study by researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and the OSU College of Veterinary Medi

Life & Chemistry

Gene Linked to Type 2 Diabetes Discovered in Obese Mice

In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.

The finding is important because it provides evidence that the same gene in humans could provide clinicians with a powerful tool to determine the likelihood that some individuals will acquire the condition. Moreover, the finding that the gene works through a pathway not generally

Life & Chemistry

UCSD Researchers Identify Gene Linked to Meal Retardation

The research team, directed by Joseph Gleeson, M.D., Director of the Neurogenetics Laboratory at the UCSD School of Medicine and associate professor in the Department of Neurosciences, have identified a new gene that, when mutated, leads to JSRD. Their findings will be published on-line May 7 in advance of publication in the journal Nature Genetics.

JSRD is a group of neurodevelopmental syndromes marked by absence of the middle part of the cerebellum called the vermis, along with features

Life & Chemistry

White Blood Cells from Cancer-Resistant Mice Show Promise

White blood cells from a strain of cancer-resistant mice cured advanced cancers in ordinary laboratory mice, researchers at Wake Forest University School of Medicine reported today.

“Even highly aggressive forms of malignancy with extremely large tumors were eradicated,” Zheng Cui, M.D., Ph.D., and colleagues reported in this week’s on-line edition of Proceedings of the National Academy of Sciences.

The transplanted white blood cells not only killed existing can

Life & Chemistry

What controls stickiness of ’smart’ chromosomal glue

Researchers have a new understanding of the process cells use to ensure that sperm and eggs begin life with exactly one copy of each chromosome – a process that must be exquisitely regulated to prevent problems such as miscarriages and mental retardation. The new work reveals how gluelike protein complexes release pairs of chromosomes at precisely the moment of meiosis – the specialized cell division process that produces sperm and eggs – enabling them to separate properly.

The researchers

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