Health & Medicine

Health & Medicine

3D Molecular Sciences Unveils Patented Tool for Bioassays

3D Molecular Sciences presented a poster providing new assay data on the Company’s multiplexing enabling platform technology for molecular medicine at the BioArray Europe conference, taking place in Cambridge, UK, on 1 October 2002. The new patented assay system consists of microfabricated encoded particles of a variety of designs, attachment chemistries and a choice of readers to interpret the results.

The poster presentation, entitled Several Assay Systems Presented Using a New Patented 3

Health & Medicine

Folic Acid: A New Ally Against Heart Disease and Stroke

Folic acid is not only a safeguard against spina bifida and other birth defects in babies – it may also prevent heart disease and strokes, two of Northern Ireland’s biggest killers.

Research at the University of Ulster has shown that folic acid and three other related B-vitamins can prevent the accumulation of a high blood level of homocysteine, a new risk factor for heart disease and strokes.

The risk of high homocysteine is similar to the risk of high cholesterol – but the good

Health & Medicine

Key Molecular Discovery Advances Neurodegenerative Disease Research

Northwestern University scientists have made a key molecular discovery that has implications for a wide range of diseases characterized by the loss of nerve function, including Huntington’s, Parkinson’s, Alzheimer’s and Lou Gehrig’s diseases, cystic fibrosis and Creutzfeldt-Jakob disease, the human form of mad cow disease.

The findings, which will be published in the Oct. 1 issue of Nature Cell Biology, could lead to an understanding of how to prevent these diseases and

Health & Medicine

Over-Prescription of Cipro Fuels Antibiotic Resistance Risks

A new study heightens concerns that Cipro and related broad-spectrum antibiotics known as fluoroquinolones are being over-prescribed, accelerating bacterial resistance to the drugs and reducing their ability to treat infections.

The UCSF-led study evaluated the records of more than 13,000 patients across the country hospitalized for “community-acquired” pneumonia – pneumonia that developed before the patient was hospitalized. The researchers found that fluoroquinolones were widely prescribe

Health & Medicine

New Melanoma Prognosis Calculator Enhances Patient Care

Tool provides physicians with better understanding of survival rates to help patients make more informed treatment decisions

The following stories detail news from the current issue of Mayo Clinic Proceedings. They are intended for use as individual stories or as part of a larger story on a particular medical topic.

Mayo Clinic researchers have developed another user-friendly calculator to aid physicians in better understanding complex cancer data and helping their patients

Health & Medicine

Safer Atrial Fibrillation Treatment: Mayo Clinic’s Findings

Mayo Clinic researchers report that the risk of stroke that sometimes results from a common treatment for atrial fibrillation can be minimized when the patient takes anticoagulation medication prior to the procedure.

The researchers report on the largest single medical center experience regarding safety of elective direct current (DC) cardioversion of atrial fibrillation. DC cardioversion is the electronic restoration of the heart’s normal rhythm.

Atrial fibrillation affects mo

Health & Medicine

Kaletra®: Four Years of HIV Suppression Without Resistance

A study from The Feinberg School of Medicine has shown that the protease inhibitor lopinavir/ritonavir (Kaletra®) suppressed HIV to undetectable levels and was well tolerated through four years of treatment in patients who had not previously received antiretroviral therapy.

To date in the Kaletra® study, none of the patients has developed resistance to Kaletra® or other protease inhibitors. Kaletra® is thus far the only protease inhibitor for which resistance has not been observed in patient

Health & Medicine

Smart Urinary Catheter Enhances Oxygen Monitoring in Patients

Monitoring oxygen delivery to organs is vital for treatment of trauma and critical care patients

When treating trauma and critical care patients after severe hemorrhagic shock, hours and days count. That’s why University of Pittsburgh researchers, working with an Israeli physiology professor, saw the need to develop a “smart” urinary catheter – which is typically used for bladder drainage – that they modified in order to provide clinicians with immediate information about the amo

Health & Medicine

Levofloxacin Resistance in S. pneumoniae: TRUST 2002 Findings

Correlations of antimicrobial resistance among s. pneumoniae in the U.S.: 2001-2002 trust surveillance

Resistance to commonly prescribed antibiotics is increasing among Streptococcus pneumoniae, a leading cause of respiratory illness. In the early 1990s, resistance to penicillin became a concern, however, in the last five years (1998-2002), S. pneumoniae has also exhibited increased resistance to other antibiotic classes, such as the macrolides (e.g. azithromycin, clarithromycin) and

Health & Medicine

New Cardiac Arrest Drug: Vasopressin Gains Attention

Vasopressin as an agent for cardio-pulmonary resuscitation

Diseases of the cardiovascular system continue to be the most frequent causes of death in the Western world. For over 100 years, Adrenaline has been the standard drug of choice in the treatment of sudden cardiac arrest. A team of researchers headed by Karl H. Lindner and Volker Wenzel from the University Department of Anaesthesiology and Critical Care Medicine, University of Innsbruck, has, with the support of the Austrian Sc

Health & Medicine

UK Researchers Unveil New Outpatient Treatment for Fibroids

UK researchers have developed a novel method of treating uterine fibroids that allows women to be treated under local anaesthetic as outpatients. Their technique, which uses a laser guided by magnetic resonance imaging (MRI), is reported today (Friday 27 September) in Europe’s leading reproductive medicine journal, Human Reproduction.*

Around a quarter of women have fibroids – benign fibrous tumours – in their wombs. Many have no symptoms but others suffer heavy or prolonged periods and pain

Health & Medicine

Spermicide Gel May Heighten HIV-1 Infection Risk: Study Results

A common spermicide gel which has previously been proposed as a preventative agent against HIV-1 infection has been shown to be ineffective, according to authors of a study in this week’s issue of THE LANCET-and could actually increase HIV-1 transmission if used frequently.

Nonoxynol-9 is an inexpensive over-the-counter spermicide; laboratory studies have suggested that it could be a barrier to HIV-1 infection and other sexually transmitted diseases, although previous studies among women hav

Health & Medicine

New Hepatitis C Treatment Outperforms Standard Therapy

he New England Journal of Medicine’s Sept. 26 issue carries the first published report showing that a combination treatment with peginterferon alfa-2a (Pegasys) – a new long-acting interferon drug – and an antiviral medication is more beneficial than the standard combination therapy for people with the most-difficult-to-treat and most common strain of hepatitis C.

The large international study, headed by researchers at the University of North Carolina at Chapel Hill, is also the first p

Health & Medicine

New Insights on Lymph Node Biopsies in Early-Stage Breast Cancer

Research results from the “Era of Hope” Department of Defense Breast Cancer Research Program meeting

iopsy is the standard tool to determine whether small breast tumors have invaded nearby lymph nodes, a signal that additional therapy is called for to destroy roving cancer cells. But the traditional procedure for nodal biopsy is, itself, major surgery with serious potential complications, and many women with early-stage cancer have no biopsy or follow up therapy, putting them at risk

Health & Medicine

Right Brain Adapts Language Skills Post-Stroke, Study Finds

When a stroke affects the language areas in the left side of the brain, the right side takes over and learns how to perform language tasks, according to research at Washington University School of Medicine in St. Louis. The study found that patients’ right side of the brain is more active than normal during a verbal language task, and that the right side’s activity decreases with practice, similar to what happens on the left side of the brain in healthy individuals.

“This is the f

Health & Medicine

Jackson Researchers Identify Gene That Protects Neurons from Oxidative Stress

Oxidative stress is implicated in a fast-growing list of human conditions, from the superficial (e.g., wrinkled skin) to the deadly: diseases such as cancer, heart disease and neurodegenerative disorders including Lou Gehrig’s disease (amyotrophic lateral sclerosis or ALS).

Researchers at The Jackson Laboratory announced that they have located a gene that protects certain brain and retinal neurons from oxidative stress, and prevents neurodegeneration.

Many normal metabolic func

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