Through their basic research, physicians at the Heart Center of the University Hospital Bonn have discovered how the communication between individual cells can be influenced with the help of a specific protein. These findings are an important approach to improving the treatment of diseases such as arteriosclerosis (calcified blood vessels), which causes heart attacks. The study was published online in advance in the “Journal of Extracellular Vesicles”, the printed version will be published shortly. The human body consists of an…
One-of-a-kind video shows how bacterium annihilates the body’s immune cells. The tuberculosis bacterium has been around as long as mankind has. To fight the bacterium, we need to know how it attacks the body’s immune system. Researchers at the Norwegian University of Science and Technology (NTNU) have taken the next step toward that goal by filming the process. It’s thought that every fourth person harbors tuberculosis bacteria in their body, although only five to ten percent of the infected population…
When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before age 25. Now, a study published by a new faculty member at Cincinnati Children’s reports a potential therapeutic target that might promote heart cell regeneration even before birth. Details were published online Aug. 17, 2020, in Cell Stem Cell. ATLAS PROVIDES DEEP LOOK…
To increase their endurance, competitive athletes often train under oxygen-deficient conditions. This is traditionally conducted in select mountain regions,…
Huntington disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of…
Understanding how exactly amyloid fibrils form is crucial for gaining insights into the development of such diseases and for advancing with treatment…
Cancer immunotherapies make use of the ability of the immune system to attack cancer cells: they unleash the killer function of T cells, which then attack and…
Cancer is the second most common cause of death worldwide. Cancers of the digestive system are particularly common. Slovakia ranks third in Europe for the…
With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of “synthetic lethality,” exploiting cancer-specific…
High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the…
Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT…
The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A's pro-inflammatory activity, according to a study by…
A team of scientists from the University of Cologne’s CECAD Cluster of Excellence (Cellular Stress Responses in Aging-Associated Diseases) led by Hamid Kashkar…
The study “Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure” was published in the Proceedings of…
For years, a scientific puzzle has bedeviled researchers aiming to fight Alzheimer's disease, a common and incurable form of dementia.
Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic's activity against antibiotic-resistant…
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