Researchers at Yale School of Medicine have discovered the breast cancer growth regulator sEGFR, which may be a useful tool in monitoring a patient’s responsiveness to treatment with the drug letrozole.
Published in a recent issue of the American Association of Cancer Researcher’s journal Cancer Research, the study focused on how decreased concentrations of sEGFR can indicate the effectiveness of letrozole.
In women with postmenopausal breast cancer, the ho
A blood test for thyroid cancer can detect persistent or recurrent disease even before doctors can find any trace of a tumor, according to a new study. The findings suggest that people treated for the disease should be examined regularly for early signs of recurrence.
The study, by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSU CCC – James), examined how well a test for thyro
A wide-ranging new international study across all disciplines has found that over 80 per cent of academic researchers the world over would willingly comply with a mandate to deposit copies of their articles in an institutional repository.
The findings of the study, carried out by Key Perspectives Ltd, for the Joint Information Systems Committee (JISC) in the UK, have been greeted by Southampton’s Professor Stevan Harnad as ‘a historic turning point in the worldwide research communi
New research suggests that the way baby girls develop in the womb may affect whether or not they develop polycystic ovarian syndrome (PCOS)* as adults and the severity of the symptoms if they do.
This major population study examines maternal factors during pregnancy and their impact on the subsequent development of PCOS, and is the first to reconcile previous conflicting research on the developmental origins of the syndrome.
Dr Michael Davies, senior research fellow
The route to a treatment for Alzheimer’s disease may have become more straightforward with the discovery that a key enzyme known to have a major role in this disease is in fact part of a family of enzymes. Only some family members play a role in the progression of this brain-wasting illness, new research at the University of Toronto has found.
“It was previously thought that an enzyme called gamma-secretase contributed to the development of protein deposits in the Alzheimer&#
When people hear “thalidomide,” many think “birth defects,” however, evidence has come to light that this once-banned drug can be used as a potent anti-cancer treatment. In a new study, researchers from the University of Bologna, Italy, demonstrate that Thal-Dex (thalidomide used in combination with dexamethasone) is more powerful than conventional chemotherapy for the treatment of multiple myeloma. Their findings will be published in the July 1, 2005, issue of Blood, the official journal of the Am
Yet another proven benefit of tight glucose control for those with type 1 diabetes
New study results confirm, for the first time, that intensive treatment of diabetic patients results in a significantly lower risk of heart disease. In fact, it can cut the risk of cardiovascular disease nearly in half. Researchers say this is yet another proven benefit of the long-term effects of tight glucose control in patients with type 1 diabetes.
The new finding was announced on Sunda
Also helps understand role of kidneys in hypertension
In related discoveries with far-reaching implications for treating diabetes and understanding hypertension, University of Utah researchers have learned why thiazolidinediones (TZDs), a major anti-diabetes drug, cause edema and also have found a new pathway critical to fluid metabolism. Identification of this pathway may help understand fundamental mechanisms of blood pressure control.
Using knockout-gene technology,
Ever stood on the tee and as you feel the eyes on the other golfers on you, your heart starts to race, your palms become sweaty, and you worry about making a mess of the shot? If this has happened, you are experiencing performance stress. A new study from the University of Alberta shows the strategies that elite golfers use to manage performance stress effectively.
A study of 18 of Ireland’s best young international male golfers aged 14 to 21 revealed differences between go
Twelve women recently completed 60 days of voluntary bedrest in order to simulate the physiological effects of weightlessness on the human body. The research team in Toulouse, France, is now actively seeking twelve new volunteers to enable them to continue and enhance the research.
At the beginning of June, the twelve volunteers from the first phase of the WISE study (Women International Simulation Experiment), were progressively ’released’ as they were gradually returne
New findings from a Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people, and prompt a major change in way TB testing is routinely done in the developing world.
Writing in the journal, “Clinical Infectious Diseases,” researchers found that while the co-existence of HIV and TB is well-known, traditional screening methods for TB are allowing significant number of cases of subclinical, active tuberculosis
South America has the most biodiversity of any major region today and according to an international team of researchers, that biodiversity began at least 52 million years ago.
“What defines terrestrial ecology is plant insect interactions,” says Dr. Peter Wilf, assistant professor of geosciences and the John T. Ryan Jr. Faculty Fellow. “But there is very little information about the history of insects eating plants in South America, despite the tremendous number of plant and an
A study of fossils from the Paleozoic Era, collected across the world, reveals that ancient brachiopods were little bothered by predators. However, the rare predation traces left on brachiopod shells by unknown assailants coupled with a subtle increase in their frequency through time may be the shadows on the wall that show killers were in the room and their numbers increased with time.
From 550 million years ago until 250 million years ago, brachiopods, or “lampshells,” were pl
Contrary to what many people believe, preschool children do not adjust how much they eat in response to how much they ate at their last meal or in the past 24 hours or how calorie-rich their meal is. By far, the most powerful predictor for how much children eat is how much food is put on their plate, concludes a new study by Cornell University researchers.
“We examined all the predictors we could of how much a child eats at a meal,” said David Levitsky, professor of nutrition
The first multinational study to assess patients considered to have diagnostic criteria for Restless Legs Syndrome (RLS), a chronic and disruptive neurological disorder characterized by a compelling urge to move the legs, found that the condition is common, under-diagnosed, and can significantly impact sleep and daily activities. Results of the R.E.S.T. (RLS Epidemiology, Symptoms, and Treatment) General Population Study, a population-based survey completed by telephone and face-to-face interviews
Even though previous research has shown that fatty acids from fish oil reduce the risk of sudden cardiac death, patients with implantable defibrillators who took fish oil supplements did not see a reduction in serious heart rhythm abnormalities, according to a study in the June 15 issue of JAMA.
Since the original observations that Greenland Eskimos eating a diet high in omega-3 polyunsaturated fats (PUFAs) from sea mammals and fish had an unexpectedly low risk of cardiac death,
Feedback
