Increased publishing in peer-reviewed journals could impact patient care, outcome; researchers need commitment, set time devoted to effort
Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals – a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out on Mon.,
Adult patients taking the antidepressant drug paroxetine are at higher risk of attempting to commit suicide than those not taking medication. A new analysis, published in BMC Medicine, of previous clinical data on paroxetine use adds the antidepressant to the list of Selective Serotonin Reuptake Inhibitors (SSRIs) that have been shown to increase suicidal tendencies in adult patients with depression.
Ivar Aursnes and colleagues from the University of Oslo, Norway, reanalysed data from 16
Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.
They say that levels of the protein produced by this suspected oncogene, known as atypical protein kinase C iota (PKCi), in combination with a second protein, Cyclin E, strongly predict outcome in non-serous ovarian cancer, which accounts for 40 percent of ovarian cancer
Epidemiological survey study links heart protection with non-aspirin, non-steroidal drugs
It is well known that aspirin, a non-selective, non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX), reduces the risk of heart attack and stroke. Non-aspirin non-steroidal anti-inflammatory drugs (NANSAIDs) such as ibuprofen and naproxen may reduce this same risk, but studies have shown conflicting results. Some have shown no association between NANSAIDs and heart
May help identify heart disease in patients who have no symptoms
The Mayo Clinic research report appears online and in the August issue of the American Journal of Hypertension. The Mayo Clinic collaborative study with researchers from the University of Michigan looked at 214 men and women with an average age of 59, who had no history of heart attack or stroke. Results suggest that low grade inflammation is associated with arterial stiffness (hardening). This inflammation may be a
Children who survive brain cancer struggle for years with the malevolent echo of the disease and its treatment, according to a new study from the Stanford University School of Medicine and Lucile Packard Children’s Hospital. Nearly one-third of former brain tumor patients require special education services, and many suffer from chronic headaches, nausea and seizures. Only about half of those old enough to drive do so.
Those who received radiation to cure their cancers fare
New research has provided further support for UK Prime Minister Tony Blair’s call for Europe’s Common Agricultural Policy (CAP) to be reformed. It concludes that the current distribution of over 90 billion Euros in farming subsidies will lead to even greater inequalities between rich and poor regions of Europe.
In the first comprehensive study of the effect of CAP on Europe’s regions, a team from the Universities of Newcastle upon Tyne and Aberdeen found that, eve
When it’s dry, it’s dry all over, according to a new analysis of more than 400 years of annual streamflow in the Upper Colorado and Salt and Verde river basins.
By using data from tree rings, University of Arizona researchers conclude that water supply for those western rivers fluctuated in synchrony during periods of severe drought. The study goes back almost 800 years in the Salt-Verde basin and covers waterways from the states of Arizona, Colorado, New Mexico, Utah and Wyoming.
Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.
Their study in the August issue of Mayo Clinic Proceedings is a preliminary look at one aspect affecting the health of patients who undergo hemodialysis. In the study, they found patients who had a higher level of adverse outcomes also had elevated levels of h
Since 1990 lions have killed more than 563 Tanzanians, including nursing mothers, children playing outside their huts and people dragged from their beds. Consequently, increasing numbers of lions are being killed by local people. In an effort to find a way to protect both people and lions, University of Minnesota researchers have analyzed the factors involved in attacks and identified the control of bush pigs — a major agricultural pest — as the most promising strategy for curbing attacks. The res
The impact of overtime and long work hours on occupational injuries and illnesses: new evidence from the United States.
The long working hours culture drives up the risk of injury and illness, reveals a study in Occupational and Environmental Medicine. And the risk has nothing to do with how hazardous the job is, conclude the researchers.
The US researchers analysed the responses of almost 11,000 Americans to the annual National Longitudinal Survey of Youth. The surv
A geographer at the University of Liverpool has discovered how women’s attitudes towards their body change in different shopping environments.
Dr Rachel Colls says size and colour of shop changing rooms, as well as the position and size of shop mirrors, influence women’s perception of their bodies.
She explains: “Research into women’s relationship with their bodies tends to find that clothes shopping and subsequent diets have negative effects on their
A paper published in the recent issue of Psychophysiology describes differences in the brain’s response (event-related potentials, or “ERPs”) to pictures and words that describe the same object. In two studies, the authors evaluated how the brain reacts differently to a picture of an object or its name when people were looking for either the picture or the name in a visual display.
University students saw pictures of five simple objects and words corresponding to their names.
Baby-boomers have spent more years living with more obesity than the previous generation, researchers at Beth Israel Deaconess Medical Center (BIDMC) have found. Although it may be too early to tell whether this will lead to a rise in arthritis rates, the study shows more obesity-related arthritis among baby boomers compared to the previous generation.
The study, published in the September issue of the American Journal of Public Health, concluded that obesity rates grew substantially fo
Results of first large international study of acute renal failure in the ICU published in JAMA
In the first multinational study of acute renal failure (ARF) in ICU patients, an international group of researchers has found that a surprisingly high number of intensive care patients – one in 20 – develop a severe form of ARF, and an alarmingly high number of those patients will die in the hospital. The study is published in the August 17 issue of the Journal of the American Medical
Overweight children who can shed their puppy fat by age 14 can expect lower blood pressure, according to a University of Queensland study.
About 2794 children in Brisbane for the study had their blood pressure and body mass or fat index (weight in kilograms divided by height in metres square) recorded at age five then at 14.
Lead researcher, Dr Abdullah Al Mamun from UQ’s School of Population Health found children who were overweight at both ages or at age 14, had avera
Feedback
